(Q30305651)

16 June 2017

title

A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity (English)

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16 June 2017

Bryan TM

1

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16 June 2017

Goodrich KJ

series ordinal

2

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16 June 2017

Cech TR

series ordinal

3

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16 June 2017

language of work or name

English

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publication date

1 August 2000

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Journal of Biological Chemistry

16 June 2017

published in

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16 June 2017

volume

275

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16 June 2017

issue

31

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16 June 2017

page(s)

24199-24207

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Structure and function of telomeres

16 June 2017

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A survey of telomerase activity in human cancer

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Inhibition of telomerase limits the growth of human cancer cells.

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The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

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Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang

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Human telomerase contains evolutionarily conserved catalytic and structural subunits

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Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

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Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA

21 January 2018

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Molecular cloning and characterization of AtTERT, a telomerase reverse transcriptase homolog in Arabidopsis thaliana

21 January 2018

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Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Telomerase is processive

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21 January 2018

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21 January 2018

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Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif

21 January 2018

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Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center.

21 January 2018

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21 January 2018

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

21 January 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate

21 January 2018

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Inhibition of telomerase by G-quartet DNA structures

21 January 2018

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21 January 2018

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dGTP-dependent processivity and possible template switching of euplotes telomerase

21 January 2018

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Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation

21 January 2018

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The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers

21 January 2018

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Developmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties

21 January 2018

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Developmentally programmed healing of chromosomes by telomerase in Tetrahymena

21 January 2018

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21 January 2018

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A reiterative mode of DNA synthesis adopted by HIV-1 reverse transcriptase after a misincorporation

21 January 2018

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Effect of dGTP concentration on human and CHO telomerase

21 January 2018

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Regulation of catalytic activity and processivity of human telomerase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M003246200

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation

21 January 2018

1 reference

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Telomerase from Saccharomyces cerevisiae contains several protein subunits and may have different activities depending on the protein content

21 January 2018

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Dynamics of telomere length variation in tetrahymena thermophila

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M003246200

1 reference

16 June 2017

1 reference