(Q30317729)

17 June 2017

title

An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms (English)

1 reference

17 June 2017

Mike Schutkowski

10

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Clemens Steegborn

11

object named as

Clemens Steegborn

1 reference

17 June 2017

David Rauh

1

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17 June 2017

Frank Fischer

2

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17 June 2017

Melanie Gertz

3

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17 June 2017

Mahadevan Lakshminarasimhan

4

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17 June 2017

Tim Bergbrede

5

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17 June 2017

Firouzeh Aladini

6

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17 June 2017

Christian Kambach

7

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17 June 2017

Christian F W Becker

8

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17 June 2017

Johannes Zerweck

9

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17 June 2017

language of work or name

English

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publication date

1 January 2013

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17 June 2017

published in

Nature Communications

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17 June 2017

volume

4

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17 June 2017

page(s)

2327

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Cell biology. Rise of the rival

17 June 2017

cites work

1 reference

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

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Sirtuins--novel therapeutic targets to treat age-associated diseases

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

21 January 2018

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

21 January 2018

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Human SIRT6 promotes DNA end resection through CtIP deacetylation

21 January 2018

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Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

21 January 2018

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Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice

21 January 2018

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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

21 January 2018

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

21 January 2018

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SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

21 January 2018

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Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia

21 January 2018

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Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

21 January 2018

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

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Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

21 January 2018

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The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

21 January 2018

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Structural basis for sirtuin function: what we know and what we don't

21 January 2018

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SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity

21 January 2018

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SIRT3 substrate specificity determined by peptide arrays and machine learning

21 January 2018

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Peptide microarrays for profiling of modification state-specific antibodies

21 January 2018

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Activation of a unique p53-dependent DNA damage response

21 January 2018

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Cytoplasm-localized SIRT1 enhances apoptosis

21 January 2018

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SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions

21 January 2018

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Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

21 January 2018

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Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis

21 January 2018

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

21 January 2018

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SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

21 January 2018

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A mitochondrial protein compendium elucidates complex I disease biology

21 January 2018

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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

21 January 2018

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

21 January 2018

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After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders

21 January 2018

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Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition

21 January 2018

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The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution

21 January 2018

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HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

21 January 2018

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Regulation of cellular metabolism by protein lysine acetylation

21 January 2018

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Regulation of sirtuin function by posttranslational modifications

21 January 2018

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Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol

21 January 2018

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Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support

21 January 2018

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Coherent membrane supports for parallel microsynthesis and screening of bioactive peptides

21 January 2018

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affy--analysis of Affymetrix GeneChip data at the probe level

21 January 2018

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Two Sample Logo: a graphical representation of the differences between two sets of sequence alignments

21 January 2018

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A continuous microplate assay for sirtuins and nicotinamide-producing enzymes

21 January 2018

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Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

21 January 2018

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Expressed protein ligation: a general method for protein engineering

21 January 2018

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Crystal structure analysis of human Sirt2 and its ADP-ribose complex

21 January 2018

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Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

21 January 2018

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Structure and biochemical functions of SIRT6.

21 January 2018

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Crystal structures of human SIRT3 displaying substrate-induced conformational changes

21 January 2018

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The Structural Basis of Sirtuin Substrate Affinity†,‡

21 January 2018

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SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

21 January 2018

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7 January 2021

The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3327

7 January 2021

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3327

7 January 2021

Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc

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7 January 2021

Structure-based development of novel sirtuin inhibitors

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NCOMMS3327

1 reference

Dimensions Publication ID

17 June 2017

0 references

1029801813

0 references

1 reference