(Q30331397)

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The reverse transcriptase sequence of human immunodeficiency virus type 1 is under positive evolutionary selection within the central nervous system.

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Europe PubMed Central

PubMed publication ID

18 June 2017

The reverse transcriptase sequence of human immunodeficiency virus type 1 is under positive evolutionary selection within the central nervous system. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

author name string

Kelly J Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

Gerald M Alter

2

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

Dawn P Wooley

3

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

publication date

1 August 2002

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

Journal of NeuroVirology

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

281-294

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection of primary human microglia and monocyte-derived macrophages with human immunodeficiency virus type 1 isolates: evidence of differential tropism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 V3 domain variation in brain and spleen of children with AIDS: tissue-specific evolution within host-determined quasispecies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling ribose selection to fidelity of DNA synthesis. The role of Tyr-115 of human immunodeficiency virus type 1 reverse transcriptase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical-neuropathologic correlation in HIV-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived HIV-1 tat sequences from AIDS patients with dementia show increased molecular heterogeneity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active HIV-1 redistribution and replication in the brain with HIV encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic approach for identifying critical residues in the fingers and palm subdomains of HIV-1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic variation of human immunodeficiency virus type 1 (HIV-1): molecular analyses of HIV-1 in sequential blood samples and various organs obtained at autopsy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of murine leukemia virus reverse transcriptase deoxyribonucleoside triphosphate-binding site in retroviral replication and in vivo fidelity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 env sequence variation in brain tissue of patients with AIDS-related neurologic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fidelity analysis of HIV-1 reverse transcriptase mutants with an altered amino-acid sequence at residues Leu74, Glu89, Tyr115, Tyr183 and Met184.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HTLV-III infection in brains of children and adults with AIDS encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of a source of HIV type 1 within the central nervous system by ultraintensive sampling of cerebrospinal fluid and plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurologic manifestations of AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 LTR DNA sequence variation in brain-derived isolates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in pathological findings at autopsy in AIDS cases for the last 15 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal comparison of HIV-1 RNA burden in plasma and cerebrospinal fluid in two patients starting triple combination antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 long terminal repeat quasispecies differ in basal transcription and nuclear factor recruitment in human glial cells and lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and cerebrospinal fluid human immunodeficiency virus type-1 (HIV-1) RNA levels in HIV-related cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological changes in early HIV-1 dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sequence alignment with Clustal X

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of ENV V3 sequences from HIV-1-infected brain indicates restrained virus expression throughout the disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 genetic evolution in children with different rates of development of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mosaic structure of the human immunodeficiency virus type 1 genome infecting lymphoid cells and the brain: evidence for frequent in vivo recombination events in the evolution of regional populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cerebrospinal fluid ganglioside GM1 concentrations indicating neuronal involvement in all stages of HIV-1 infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct HIV-1 env Sequences Are Associated with Neurotropism and Neurovirulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12161813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/13550280290100716

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 June 2017

ResearchGate publication ID

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