(Q30352054)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16321039%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100 m3 fermentation scale for an influenza pandemic (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16321039%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

0 references

3

1 reference

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9 January 2020

author name string

Mike Hoare

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16321039%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

M Susana Levy

2

1 reference

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9 January 2020

Steven D Doig

4

1 reference

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9 January 2020

Simyee Kong

5

1 reference

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9 January 2020

Nigel Titchener-Hooker

6

1 reference

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9 January 2020

John M Ward

7

1 reference

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9 January 2020

Peter Dunnill

8

1 reference

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9 January 2020

publication date

1 November 2005

1 reference

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9 January 2020

published in

Biotechnology Progress

1 reference

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9 January 2020

volume

21

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9 January 2020

issue

6

1 reference

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9 January 2020

page(s)

1577-1592

1 reference

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Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

9 January 2020

cites work

1 reference

12 December 2020

Large-scale capture and partial purification of plasmid DNA using anion-exchange membrane capsules

1 reference

12 December 2020

Purification of pharmaceutical-grade plasmid DNA by anion-exchange chromatography in an RNase-free process.

1 reference

12 December 2020

Avian flu special: avian flu: are we ready?

1 reference

12 December 2020

Hypersensitivity reactions to non-beta-lactam antibiotics

1 reference

12 December 2020

The impact of fluid-dynamic-generated stresses on chDNA and pDNA stability during alkaline cell lysis for gene therapy products

1 reference

12 December 2020

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1 reference

12 December 2020

Membrane chromatography of DNA: conformation-induced capacity and selectivity.

1 reference

12 December 2020

Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography

1 reference

12 December 2020

Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications

1 reference

12 December 2020

Shear degradation of DNA

1 reference

12 December 2020

Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004.

1 reference

12 December 2020

Hypersensitivity Reactions to Beta-Lactam Antibiotics

1 reference

12 December 2020

Physical stability of nonviral plasmid-based therapeutics

1 reference

12 December 2020

Manufacturing and quality control of plasmid-based gene expression systems

1 reference

12 December 2020

Nucleic acid separations utilizing immobilized metal affinity chromatography

1 reference

12 December 2020

Studies on the Batch Adsorption of Plasmid DNA onto Anion-Exchange Chromatographic Supports

1 reference

12 December 2020

Effects of fermentation strategy on the characteristics of plasmid DNA production

1 reference

12 December 2020

Scale-down of continuous filtration for rapid bioprocess design: Recovery and dewatering of protein precipitate suspensions.

1 reference

12 December 2020

DNA vaccination against respiratory influenza virus infection

1 reference

12 December 2020

A rapid boiling method for the preparation of bacterial plasmids

1 reference

12 December 2020

Anion exchange purification of plasmid DNA using expanded bed adsorption.

1 reference

12 December 2020

Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines.

1 reference

12 December 2020

Analysis of plasmid DNA from a pharmaceutical perspective

1 reference

12 December 2020

Chromatography of plasmid DNA.

1 reference

12 December 2020

Purification of essentially RNA free plasmid DNA using a modified Escherichia coli host strain expressing ribonuclease A.

1 reference

12 December 2020

A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans

1 reference

12 December 2020

Influence of scale-up on the quality of recombinant human growth hormone

1 reference

12 December 2020

Monitoring of RNA clearance in a novel plasmid DNA purification process

1 reference

12 December 2020

The annual production cycle for influenza vaccine

1 reference

12 December 2020

Large-scale purification of recombinant human angiostatin

1 reference

12 December 2020

Scaleable processes for the manufacture of therapeutic quantities of plasmid DNA.

1 reference

12 December 2020

A mass balance study to assess the extent of contaminant removal achieved in the operations for the primary recovery of plasmid DNA from Escherichia coli cells.

1 reference

12 December 2020

Precipitation of RNA impurities with high salt in a plasmid DNA purification process: use of experimental design to determine reaction conditions.

1 reference

12 December 2020

Impact of engineering flow conditions on plasmid DNA yield and purity in chemical cell lysis operations.

1 reference

12 December 2020

Quantitation of supercoiled circular content in plasmid DNA solutions using a fluorescence-based method

1 reference

12 December 2020

Extraction of plasmid DNA using reactor scale alkaline lysis and selective precipitation for scalable transient transfection

1 reference

12 December 2020

Further studies related to the scale-up of high cell density Escherichia coli fed-batch fermentations: the additional effect of a changing microenvironment when using aqueous ammonia to control pH.

1 reference

12 December 2020

Fractional precipitation of plasmid DNA from lysate by CTAB.

1 reference

12 December 2020

Scale-up methodologies for Escherichia coli and yeast fermentation processes

1 reference

12 December 2020

Influenza: girding for disaster. Facing down pandemic flu, the world's defenses are weak

1 reference

12 December 2020

Evaluation of an ion‐exchange membrane for the purification of plasmid DNA

1 reference

12 December 2020

Effective and robust plasmid topology analysis and the subsequent characterization of the plasmid isoforms thereby observed

1 reference

12 December 2020

Influenza DNA vaccines

1 reference

12 December 2020

DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice.

1 reference

12 December 2020

Purification of plasmid DNA by an integrated operation comprising tangential flow filtration and nitrocellulose adsorption

1 reference

12 December 2020

Size fractionation of double-stranded DNA by precipitation with polyethylene glycol

1 reference

12 December 2020

Advances in vaccine adjuvants

1 reference

12 December 2020

The epidemiology and clinical impact of pandemic influenza.

1 reference

12 December 2020

Characterization of the metabolic burden on Escherichia coli DH1 cells imposed by the presence of a plasmid containing a gene therapy sequence

1 reference

12 December 2020

DNA vaccines: a review

1 reference

12 December 2020

Public health. Will vaccines be available for the next influenza pandemic?

1 reference

12 December 2020

Solubilization and binding of DNA-CTAB complex with SDS in aqueous media

1 reference

12 December 2020

Cationic microparticles: A potent delivery system for DNA vaccines

1 reference

12 December 2020

Extracellular enzyme loss during polyelectrolyte flocculation of cells from fermentation broth

1 reference

12 December 2020

An automated microplate-based method for monitoring DNA strand breaks in plasmids and bacterial artificial chromosomes

1 reference

12 December 2020

Purification of plasmid DNA with a new type of anion-exchange beads having a non-charged surface

1 reference

12 December 2020

Automated fed-batch fermentation with feed-back controls based on dissolved oxygen (DO) and pH for production of DNA vaccines.

1 reference

12 December 2020

Regional antibody and cellular immune responses to equine influenza virus infection, and particle mediated DNA vaccination.

1 reference

12 December 2020

Cross-flow membrane microfiltration of a bacteriol fermentation broth

1 reference

12 December 2020

Preparing for pandemic vaccination: an international policy agenda for vaccine development.

1 reference

12 December 2020

Harvesting recombinant microbial cells using crossflow filtration

1 reference

12 December 2020

Biochemical engineering approaches to the challenges of producing pure plasmid DNA.

1 reference

12 December 2020

Purification of plasmid DNA by tangential flow filtration

1 reference

12 December 2020

Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines.

1 reference

12 December 2020

Time course of SDS-alkaline lysis of recombinant bacterial cells for plasmid release

1 reference

12 December 2020

Plasmid DNA purification by selective calcium silicate adsorption of closely related impurities.

1 reference

12 December 2020

Removal of RNA impurities by tangential flow filtration in an RNase-free plasmid DNA purification process

1 reference

12 December 2020

Impact of plasmid size on cellular oxygen demand in Escherichia coli

1 reference

12 December 2020

Effects of growth medium selection on plasmid DNA production and initial processing steps

1 reference

12 December 2020

Analysis and simulation of complex interactions during dynamic microfiltration of Escherichia coli suspensions

1 reference

12 December 2020

Design of expanded bed supports for the recovery of plasmid DNA by anion exchange adsorption

1 reference

12 December 2020

Animal-free production of ccc-supercoiled plasmids for research and clinical applications

1 reference

12 December 2020

Probable person-to-person transmission of avian influenza A (H5N1)

1 reference

12 December 2020

Identifiers

DOI

10.1021/BP050190N

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16321039%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PMC publication ID

7161863

0 references

1 reference