(Q30363065)

9 October 2017

Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate. (English)

1 reference

9 October 2017

computational biology

0 references

author

Yoonjoo Choi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Karl E. Griswold

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

5

Chris Bailey-Kellogg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Regina S Salvat

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Andrew S Parker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Andrew Guilliams

3

1 reference

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5 June 2020

publication date

1 June 2014

1 reference

Cellular and Molecular Life Sciences

9 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

24

1 reference

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5 June 2020

page(s)

4869-4880

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00018-014-1652-x

5 June 2020

exact match

0 references

cites work

A high throughput MHC II binding assay for quantitative analysis of peptide epitopes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

The functional importance of co-evolving residues in proteins.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Structure-guided deimmunization of therapeutic proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Structure-based redesign of proteins for minimal T-cell epitope content

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Design and analysis of immune-evading enzymes for ADEPT therapy.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Immunogenicity of protein therapeutics: The key causes, consequences and challenges

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Immunogenicity of biotherapeutics in the context of developing biosimilars and biobetters

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

High throughput T epitope mapping and vaccine development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Optimization algorithms for functional deimmunization of therapeutic proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Engineering and biological characterization of VB6-845, an anti-EpCAM immunotoxin containing a T-cell epitope-depleted variant of the plant toxin bouganin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Reducing the immunogenicity of protein therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Understanding the focused CD4 T cell response to antigen and pathogenic organisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

New approaches to prediction of immune responses to therapeutic proteins during preclinical development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Immunogenicity of protein therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

SVRMHC prediction server for MHC-binding peptides

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

De-immunization of therapeutic proteins by T-cell epitope modification.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

A beta-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Factors influencing the immunogenicity of therapeutic proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Cell biology of antigen processing in vitro and in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

The relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse model

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Several common HLA-DR types share largely overlapping peptide binding repertoires

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Oligopeptide biases in protein sequences and their use in predicting protein coding regions in nucleotide sequences

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

ProPred: prediction of HLA-DR binding sites.

3 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Automated generation and evaluation of specific MHC binding predictive tools: ARB matrix applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Rationally engineered therapeutic proteins with reduced immunogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

Implications of available design space for identification of non-immunogenic protein therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1652-X

MHCPred: bringing a quantitative dimension to the online prediction of MHC binding.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4234684

Elimination of a human T-cell region in staphylokinase by T-cell screening and computer modeling

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24880662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00018-014-1652-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880662%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

24880662

1 reference