(Q37386987)

20 August 2017

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title

Understanding the focused CD4 T cell response to antigen and pathogenic organisms (English)

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20 August 2017

Jason M Weaver

1

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20 August 2017

Andrea J Sant

series ordinal

2

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20 August 2017

publication date

7 February 2009

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20 August 2017

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20 August 2017

volume

45

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20 August 2017

issue

2-3

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20 August 2017

page(s)

123-143

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Reversal of immunodominance among autoantigenic T-cell epitopes

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Insertion of the dibasic motif in the flanking region of a cryptic self-determinant leads to activation of the epitope-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Sorting of furin in polarized epithelial and endothelial cells: expression beyond the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

The distinctive features of influenza virus infection of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Several protein regions contribute to determine the nuclear and cytoplasmic localization of the influenza A virus nucleoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

The impact of H2-DM on humoral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Differential immunogenicity of various heterologous prime-boost vaccine regimens using DNA and viral vectors in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8095-8

Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays

21 January 2018

1 reference

12 December 2020

Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection

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12 December 2020

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

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12 December 2020

Novel features of the respiratory tract T-cell response to influenza virus infection: lung T cells increase expression of gamma interferon mRNA in vivo and maintain high levels of mRNA expression for interleukin-5 (IL-5) and IL-10.

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12 December 2020

The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules

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12 December 2020

Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity

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12 December 2020

Immunodominance: a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants

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12 December 2020

MHC class II-restricted presentation of intracellular antigen

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12 December 2020

Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.

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12 December 2020

Three dimensional structure directs T-cell epitope dominance associated with allergy

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12 December 2020

Mediation by HLA-DM of dissociation of peptides from HLA-DR

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12 December 2020

Quantitation of CD8+ T cell responses to newly identified HLA-A*0201-restricted T cell epitopes conserved among vaccinia and variola (smallpox) viruses

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12 December 2020

Endogenous antigen presentation by MHC class II molecules.

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12 December 2020

The relative energetic contributions of dominant P1 pocket versus hydrogen bonding interactions to peptide:class II stability: implications for the mechanism of DM function

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12 December 2020

Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells

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12 December 2020

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

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12 December 2020

The proprotein convertases

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12 December 2020

Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential

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12 December 2020

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

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12 December 2020

Harnessing bioinformatics to discover new vaccines

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12 December 2020

Cutting edge: introduction of an endopeptidase cleavage motif into a determinant flanking region of hen egg lysozyme results in enhanced T cell determinant display

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12 December 2020

Editing of the HLA-DR-peptide repertoire by HLA-DM

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12 December 2020

Accelerated migration of respiratory dendritic cells to the regional lymph nodes is limited to the early phase of pulmonary infection

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12 December 2020

Immunization with a synthetic multiepitope antigen induces humoral and cellular immune responses to hepatitis C virus in mice

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12 December 2020

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

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12 December 2020

HLA-DM and the MHC class II antigen presentation pathway

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12 December 2020

Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

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12 December 2020

Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.

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12 December 2020

Time Course of Synthesis and Assembly of Influenza Virus Proteins

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12 December 2020

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression

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12 December 2020

Nuclear import and export of influenza virus nucleoprotein.

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12 December 2020

Immune epitope mapping in the post-genomic era: lessons for vaccine development

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12 December 2020

Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

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12 December 2020

Protein sorting within the MHC class II antigen-processing pathway

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12 December 2020

Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses

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12 December 2020

Role of APC in the selection of immunodominant T cell epitopes.

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12 December 2020

Selection of the MHC class II-associated peptide repertoire by HLA-DM.

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12 December 2020

Synthesis and function of influenza A virus glycoproteins

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12 December 2020

Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

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12 December 2020

Role of amino acid sequences flanking dibasic cleavage sites in precursor proteolytic processing. The importance of the first residue C-terminal of the cleavage site

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12 December 2020

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

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12 December 2020

DM determines the cryptic and immunodominant fate of T cell epitopes

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12 December 2020

Dominance and crypticity of T cell antigenic determinants

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12 December 2020

HLA-DM, HLA-DO and tapasin: functional similarities and differences

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12 December 2020

Epitope-based vaccines: an update on epitope identification, vaccine design and delivery

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12 December 2020

Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes

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12 December 2020

Helper T-cell Epitope Immunodominance Associated with Structurally Stable Segments of Hen Egg Lysozyme and HIV gp120

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12 December 2020

A Bayesian regression approach to the prediction of MHC-II binding affinity

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12 December 2020

Heterogeneity of the T cell response to immunodominant determinants within hen eggwhite lysozyme of individual syngeneic hybrid F1 mice: implications for autoimmunity and infection.

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12 December 2020

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

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12 December 2020

Energetic asymmetry among hydrogen bonds in MHC class II*peptide complexes

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12 December 2020

Measurement of peptide dissociation from MHC class II molecules

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12 December 2020

Direct class I HLA antigen discovery to distinguish virus-infected and cancerous cells

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12 December 2020

Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein

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12 December 2020

The function of local lymphoid tissues in pulmonary immune responses

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12 December 2020

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

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12 December 2020

Interference with the binding of a naturally processed peptide to class II alters the immunodominance of T cell epitopes in vivo

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12 December 2020

Integrating epitope data into the emerging web of biomedical knowledge resources

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12 December 2020

T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage

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12 December 2020

Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes

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12 December 2020

Ovalbumin(323-339) peptide binds to the major histocompatibility complex class II I-A(d) protein using two functionally distinct registers

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12 December 2020

Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways

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12 December 2020

Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen

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12 December 2020

Class II-independent generation of CD4 memory T cells from effectors.

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12 December 2020

Endoproteolysis in health and diseases--implications of proprotein convertases (PCs)

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12 December 2020

Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo

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12 December 2020

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

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12 December 2020

Mechanisms influencing the immunodominance of T cell determinants

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12 December 2020

The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA

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12 December 2020

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

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12 December 2020

Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope.

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12 December 2020

Kinetics of precursor cleavage at the dibasic sites. Involvement of peptide dynamics

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12 December 2020

From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis

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12 December 2020

Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin

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12 December 2020

MODPROPEP: a program for knowledge-based modeling of protein-peptide complexes

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12 December 2020

Clustering of Th Cell Epitopes on Exposed Regions of HIV Envelope Despite Defects in Antibody Activity

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12 December 2020

Structures of an MHC class II molecule with covalently bound single peptides

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12 December 2020

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

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12 December 2020

In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

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12 December 2020

Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity

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12 December 2020

Antigen-presenting cells and the selection of immunodominant epitopes.

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12 December 2020

Impairment of immunological memory in the absence of MHC despite survival of memory T cells

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12 December 2020

The endogenous pathway of MHC class II antigen presentation.

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12 December 2020

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

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12 December 2020

Mechanisms of T cell epitope immunodominance analyzed in murine listeriosis

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12 December 2020

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

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12 December 2020

In vivo competition between self peptides and foreign antigens in T-cell activation

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12 December 2020

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

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12 December 2020

Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection

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12 December 2020

T cell recognition of myoglobin. Localization of the sites stimulating T cell proliferative responses by synthetic overlapping peptides encompassing the entire molecule

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12 December 2020

Antigen three-dimensional structure guides the processing and presentation of helper T-cell epitopes.

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12 December 2020

Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules

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12 December 2020

Antigen processing and T cell repertoires as crucial aleatory features in induction of autoimmunity

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12 December 2020

T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node

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12 December 2020

Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma

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12 December 2020

The influenza virus NS1 protein: inhibitor of innate and adaptive immunity

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12 December 2020

CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells

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12 December 2020

The convergent roles of tapasin and HLA-DM in antigen presentation.

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12 December 2020

Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design

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12 December 2020

Optimizing vaccine design for cellular processing, MHC binding and TCR recognition

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12 December 2020

Assessment of the role of determinant selection in genetic control of the immune response to insulin in H-2b mice

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12 December 2020

Modulation of the immunogenicity of antigenic determinants by their flanking residues

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12 December 2020

Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice

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12 December 2020

Epitope identification and vaccine design for cancer immunotherapy

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12 December 2020

Identification of destabilizing residues in HLA class II-selected bacteriophage display libraries edited by HLA-DM.

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12 December 2020

Functional association between viral and cellular transcription during influenza virus infection

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12 December 2020

Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif

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12 December 2020

Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing

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12 December 2020

Primary and memory T cell responses induced by hepatitis C virus multiepitope long peptides

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12 December 2020

Efficient synthesis of influenza virus hemagglutinin in mammalian cells with an extrachromosomal Epstein-Barr virus vector.

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12 December 2020

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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12 December 2020

Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infection

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12 December 2020

Occurrence of an HIV-1 gp160 endoproteolytic activity in low-density vesicles and evidence for a distinct density distribution from endogenously expressed furin and PC7/LPC convertases

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12 December 2020

Antiviral CD4+ memory T cells are IL-15 dependent

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12 December 2020

Immunodominance is independent of structural constraints: each region within hen eggwhite lysozyme is potentially available upon processing of native antigen

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12 December 2020

Control of Leishmania major by a monoclonal alpha beta T cell repertoire.

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12 December 2020

The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors

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12 December 2020

Structural basis for helper T-cell and antibody epitope immunodominance in bacteriophage T4 Hsp10. Role of disordered loops

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12 December 2020

Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell-based cancer vaccines

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12 December 2020

Functional specialization of memory Th cells revealed by expression of integrin CD49b

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12 December 2020

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

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12 December 2020

Static energy analysis of MHC class I and class II peptide-binding affinity.

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12 December 2020

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan

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12 December 2020

Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation

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12 December 2020

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

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12 December 2020

Lymphoid reservoirs of antigen-specific memory T helper cells

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12 December 2020

Individual hydrogen bonds play a critical role in MHC class II: peptide interactions: implications for the dynamic aspects of class II trafficking and DM-mediated peptide exchange

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12 December 2020

T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes

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12 December 2020

Imaging of plasmacytoid dendritic cell interactions with T cells

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12 December 2020

The involvement of antigen processing in determinant selection by class II MHC and its relationship to immunodominance

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12 December 2020

Antigen structure influences helper T-cell epitope dominance in the human immune response to HIV envelope glycoprotein gp120.

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12 December 2020

Identification of distinct predominant epitopes recognized by myoglobin-specific T cells under the control of different Ir genes and characterization of representative T cell clones

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12 December 2020

Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action

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12 December 2020

SAP-controlled T-B cell interactions underlie germinal centre formation

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12 December 2020

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

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12 December 2020

Specific antitumor immune response induced by a novel DNA vaccine composed of multiple CTL and T helper cell epitopes of prostate cancer associated antigens

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12 December 2020

Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models

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12 December 2020

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

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12 December 2020

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

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12 December 2020

How HLA-DM affects the peptide repertoire bound to HLA-DR molecules

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12 December 2020

Multiple anti-interferon actions of the influenza A virus NS1 protein

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12 December 2020

Peptide-binding motifs for the I-Ad MHC class II molecule: alternate pH-dependent binding behavior.

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12 December 2020

10.1007/S12026-009-8095-8

Identifiers

DOI

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20 August 2017

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