(Q36404572)

14 August 2017

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. (English)

1 reference

14 August 2017

C L Chou

1

1 reference

PMCID

2213500

14 August 2017

S Sadegh-Nasseri

series ordinal

2

1 reference

PMCID

2213500

14 August 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

192

1 reference

14 August 2017

12

1 reference

14 August 2017

1697-1706

1 reference

DM determines the cryptic and immunodominant fate of T cell epitopes

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Crystal structure of mouse H2-M

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Altered antigen presentation in mice lacking H2-O

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Editing of the HLA-DR-peptide repertoire by HLA-DM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Processing and presentation of endocytically acquired protein antigens by MHC class II and class I molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Structures of an MHC class II molecule with covalently bound single peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

A general model of invariant chain association with class II major histocompatibility complex proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

How MHC class II molecules work: peptide-dependent completion of protein folding.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

MHC class II function preserved by low-affinity peptide interactions preceding stable binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Mediation by HLA-DM of dissociation of peptides from HLA-DR

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Direct detection of major histocompatibility complex class I binding to antigenic peptides using surface plasmon resonance. Peptide immobilization and characterization of binding specificity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

A kinetic intermediate in the reaction of an antigenic peptide and I-Ek

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213500

Structural intermediates in the reactions of antigenic peptides with MHC molecules.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Formation of a highly peptide-receptive state of class II MHC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

A role for peptide in determining MHC class II structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Energy transfer between two peptides bound to one MHC class II molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Determination of binding constants by equilibrium titration with circulating sample in a surface plasmon resonance biosensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

Measuring interactions of MHC class I molecules using surface plasmon resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.12.1697

HLA-DM is present in one-fifth the amount of HLA-DR in the class II peptide-loading compartment where it associates with leupeptin-induced peptide (LIP)-HLA-DR complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11120767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11120767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.192.12.1697

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

PMCID

2213500