(Q30366581)

21 June 2017

1 reference

title

Topical microbicides: a promising approach for controlling the AIDS pandemic via retroviral zinc finger inhibitors. (English)

1 reference

21 June 2017

0 references

Jim A Turpin

1

1 reference

21 June 2017

Marco L Schito

2

1 reference

21 June 2017

Lisa M Miller Jenkins

3

1 reference

21 June 2017

John K Inman

4

1 reference

21 June 2017

Ettore Appella

5

1 reference

21 June 2017

publication date

1 January 2008

1 reference

21 June 2017

published in

Advances in Pharmacology

1 reference

21 June 2017

volume

56

1 reference

21 June 2017

page(s)

229-256

1 reference

Inactivation of HIV-1 nucleocapsid protein P7 by pyridinioalkanoyl thioesters. Characterization of reaction products and proposed mechanism of action.

21 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Potential metal-binding domains in nucleic acid binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Cellulose acetate 1,2-benzenedicarboxylate protects against challenge with pathogenic X4 and R5 simian/human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Factors affecting sexual transmission of HIV-1: current evidence and implications for prevention.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Spectroscopic characterization of Co(II)-, Ni(II)-, and Cd(II)-substituted wild-type and non-native retroviral-type zinc finger peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Probing the topography of HIV-1 nucleocapsid protein with the alkylating agent N-ethylmaleimide

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Amplified HIV transmission and new approaches to HIV prevention

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Development of an in vitro organ culture model to study transmissionof HIV-1 in the female genital tract

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Amino acid sequence homology in gag region of reverse transcribing elements and the coat protein gene of cauliflower mosaic virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Clinical development of microbicides for the prevention of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The role of nucleocapsid of HIV-1 in virus assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Microbicides to prevent HIV transmission: overcoming obstacles to chemical barrier protection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Shifts in condom use following microbicide introduction: should we be concerned?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The enigma of dendritic cell-immunodeficiency virus interplay

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM)

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

AIDS anniversaries in 2006 mark the time to deliver.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Zinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Subtle alterations of the native zinc finger structures have dramatic effects on the nucleic acid chaperone activity of human immunodeficiency virus type 1 nucleocapsid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

High viral load in semen of human immunodeficiency virus type 1-infected men at all stages of disease and its reduction by therapy with protease and nonnucleoside reverse transcriptase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Perils at mucosal front lines for HIV and SIV and their hosts

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Mechanistic insights into the kinetics of HIV-1 nucleocapsid protein-facilitated tRNA annealing to the primer binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Microbicides and HIV: help or hindrance?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Which topical microbicides for blocking HIV-1 transmission will work in the real world?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Interactions between HIV-1 nucleocapsid protein and viral DNA may have important functions in the viral life cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Microbicides and other topical strategies to prevent vaginal transmission of HIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Dynamical behavior of the HIV-1 nucleocapsid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Biophysical characterization of zinc ejection from HIV nucleocapsid protein by anti-HIV 2,2'-dithiobis[benzamides] and benzisothiazolones

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Cellulose acetate 1,2-benzenedicarboxylate inhibits infection by cell-free and cell-associated primary HIV-1 isolates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Reactivity of zinc finger cores: analysis of protein packing and electrostatic screening.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Human cellular nucleic acid-binding protein Zn2+ fingers support replication of human immunodeficiency virus type 1 when they are substituted in the nucleocapsid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Target cells in vaginal HIV transmission

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Water dispersible microbicidal cellulose acetate phthalate film

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The activity of candidate virucidal agents, low pH and genital secretions against HIV-1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Acid sensitivity of cell-free and cell-associated HIV-1: clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Macaca fascicularis vs. Macaca nemestrina as a model for topical microbicide safety studies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Anti-HIV drug development--an overview

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Brief but efficient: acute HIV infection and the sexual transmission of HIV.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Transmission, acute HIV-1 infection and the quest for strategies to prevent infection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

T lymphocytes and macrophages, but not motile spermatozoa, are a significant source of human immunodeficiency virus in semen

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Structural investigation on the requirement of CCHH zinc finger type in nucleocapsid protein of human immunodeficiency virus 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Induction of endonuclease-mediated apoptosis in tumor cells by C-nitroso-substituted ligands of poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

A human immunodeficiency virus-transgenic mouse model for assessing interventions that block microbial-induced proviral expression

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Affinities of packaging domain loops in HIV-1 RNA for the nucleocapsid protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

C-terminal retroviral-type zinc finger domain from the HIV-1 nucleocapsid protein is structurally similar to the N-terminal zinc finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Optimization of unique, uncharged thioesters as inhibitors of HIV replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

HIV prevention: the need for methods women can use

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Microbicides: a new approach to preventing HIV and other sexually transmitted infections

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

HIV topical microbicides: the current development strategy is fully justified

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Role of the N-terminal zinc finger of human immunodeficiency virus type 1 nucleocapsid protein in virus structure and replication

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Interactions of Azodicarbonamide (ADA) Species with the Model Zinc Finger Site: Theoretical Support of the Zinc Finger Domain Destruction in the HIV-1 Nucleocapsid Protein (NCp7) by ADA

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The next generation of HIV/AIDS drugs: novel and developmental antiHIV drugs and targets

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Phase 1 trial of the topical microbicide BufferGel: safety results from four international sites

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The importance of context: model projections on how microbicide impact could be affected by the underlying epidemiologic and behavioral situation in 2 African settings

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

The development of vaginal microbicides for the prevention of HIV transmission

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956008-4

7 January 2021

10.1016/S1054-3589(07)56008-4

Identifiers

DOI

1 reference

21 June 2017

1 reference