(Q30397539)

19 October 2017

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells (English)

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Human Induced Pluripotent Stem Cells

19 October 2017

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7

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19 October 2017

Andriana G Kotini

1

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Gregory A Fishbein

object named as

Gregory A Fishbein

8

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Danwei Huangfu

object named as

Danwei Huangfu

11

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Timothy A. Graubert

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Timothy Graubert

13

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author name string

Chan-Jung Chang

2

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19 October 2017

Ibrahim Boussaad

3

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19 October 2017

Jeffrey J Delrow

4

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19 October 2017

Emily K Dolezal

5

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19 October 2017

Abhinav B Nagulapally

6

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19 October 2017

Virginia M Klimek

9

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19 October 2017

R David Hawkins

10

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19 October 2017

Charles E Murry

12

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19 October 2017

Stephen D Nimer

14

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19 October 2017

Eirini P Papapetrou

15

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19 October 2017

23 March 2015

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19 October 2017

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19 October 2017

33

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19 October 2017

6

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19 October 2017

646-655

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describes a project that uses

19 October 2017

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4464949/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4464949

inferred from PubMed Central ID database lookup

cites work

An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

The biology and clinical impact of genetic lesions in myeloid malignancies.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Gene copy-number alterations: a cost-benefit analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Phenotypic impact of genomic structural variation: insights from and for human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Trisomy correction in Down syndrome induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Molecular pathophysiology of myelodysplastic syndromes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

The role of mutations in epigenetic regulators in myeloid malignancies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

The origin and evolution of mutations in acute myeloid leukemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Recurrent hemizygous deletions in cancers may optimize proliferative potential

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Clonal architecture of secondary acute myeloid leukemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Rare and common variants: twenty arguments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Induced pluripotent stem cells--opportunities for disease modelling and drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

A continuum model for tumour suppression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Genome structural variation discovery and genotyping

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

The landscape of somatic copy-number alteration across human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Haploid genetic screens in human cells identify host factors used by pathogens

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Computational neuroanatomy of speech production.

20 June 2018

1 reference

Generation of transgene-free human induced pluripotent stem cells with an excisable single polycistronic vector.

21 January 2018

1 reference

Cre-mediated chromosome loss in mice

21 January 2018

1 reference

Targeted chromosome elimination from ES-somatic hybrid cells.

21 January 2018

1 reference

A genetic strategy for single and combinatorial analysis of miRNA function in mammalian hematopoietic stem cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4464949

Hematopoietic progenitor cells from patients with myelodysplastic syndromes: in vitro colony growth and long-term proliferation

26 November 2018

1 reference

12 December 2020

Molecular cytogenetic characterization of a critical region in bands 7q35-q36 commonly deleted in malignant myeloid disorders

1 reference

12 December 2020

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

1 reference

12 December 2020

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

1 reference

12 December 2020

Defining the path to hematopoietic stem cells

1 reference

12 December 2020

Recurrent genetic defects on chromosome 7q in myeloid neoplasms

1 reference

12 December 2020

Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT.3178

1 reference

release_yapx7hnny5b7ppukto4od5rvla

19 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yapx7hnny5b7ppukto4od5rvla

24 November 2022

mapped directly with Wikidata item

1 reference

19 October 2017

PubMed publication ID

25798938

1 reference