(Q30400724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

Rapid analysis of pharmacology for infectious diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2 references

23 March 2019

4 August 2019

1 reference

4 August 2019

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Andrew L Hopkins

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

G Richard J Bickerton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Ian M Carruthers

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Stephen K Boyer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Harvey Rubin

5

1 reference

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25 January 2020

publication date

1 January 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

Current Topics in Medicinal Chemistry

25 January 2020

published in

3 references

23 March 2019

4 August 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

11

1 reference

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25 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

1292-1300

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.5 Generic

25 January 2020

copyright license

2 references

23 March 2019

on focus list of Wikimedia project

4 August 2019

ScienceSource

0 references

cites work

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20 June 2018

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20 June 2018

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Pathogenesis of flavivirus infections: using and abusing the host cell

20 June 2018

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A kernel for the Tropical Disease Initiative

20 June 2018

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The value of drug repositioning in the current pharmaceutical market

20 June 2018

1 reference

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Binding site detection and druggability index from first principles.

20 June 2018

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Genome-scale reconstruction of Escherichia coli's transcriptional and translational machinery: a knowledge base, its mathematical formulation, and its functional characterization

20 June 2018

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A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoni

20 June 2018

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Reconstruction of biochemical networks in microorganisms

20 June 2018

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Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity

20 June 2018

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Genome-scale models of bacterial metabolism: reconstruction and applications

20 June 2018

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Linezolid for the treatment of drug-resistant infections

20 June 2018

1 reference

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Global Bayesian models for the prioritization of antitubercular agents

20 June 2018

1 reference

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Network pharmacology: the next paradigm in drug discovery

20 June 2018

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Genomic-scale prioritization of drug targets: the TDR Targets database

20 June 2018

1 reference

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Has nature already identified all useful antibacterial targets?

20 June 2018

1 reference

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RNA interference screen for human genes associated with West Nile virus infection

20 June 2018

1 reference

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How many modes of action should an antibiotic have?

20 June 2018

1 reference

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The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

20 June 2018

1 reference

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The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases?

20 June 2018

1 reference

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Quantifying the relationships among drug classes

20 June 2018

1 reference

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Global trends in emerging infectious diseases

20 June 2018

1 reference

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A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

20 June 2018

1 reference

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Identification of host proteins required for HIV infection through a functional genomic screen

20 June 2018

1 reference

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Chemogenomic data analysis: prediction of small-molecule targets and the advent of biological fingerprint

20 June 2018

1 reference

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Mining predicted essential genes of Brugia malayi for nematode drug targets

20 June 2018

1 reference

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Molecular approaches to target discovery:--evaluating targets for anti-tuberculosis drug discovery programmes

20 June 2018

1 reference

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Late stage antibacterial drugs in the clinical pipeline

20 June 2018

1 reference

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20 June 2018

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A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information

20 June 2018

1 reference

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Assessing performance of orthology detection strategies applied to eukaryotic genomes

20 June 2018

1 reference

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Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

High-throughput electronic biology: mining information for drug discovery

20 June 2018

1 reference

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Relating protein pharmacology by ligand chemistry

20 June 2018

1 reference

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

20 June 2018

1 reference

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Multi-targeting by monotherapeutic antibacterials.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Chemogenomics: structuring the drug discovery process to gene families.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Chemogenomics: drug discovery's panacea?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Chemogenomics in drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

DrugBank: a comprehensive resource for in silico drug discovery and exploration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

MODBASE: a database of annotated comparative protein structure models and associated resources

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Predicting protein druggability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

The druggable genome: an update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Druggability indices for protein targets derived from NMR-based screening data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Virtual screening of chemical libraries

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Biochemical mechanisms of drug action: what does it take for success?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Drug repositioning: identifying and developing new uses for existing drugs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Computational chemogenomics approaches to systematic knowledge-based drug discovery.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Drug development for neglected diseases: a deficient market and a public-health policy failure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Escherichia coli mutants lacking all possible combinations of eight penicillin binding proteins: viability, characteristics, and implications for peptidoglycan synthesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Medical literature as a potential source of new knowledge

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

20 June 2018

2008 FDA drug approvals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Target-based antimicrobial drug discovery

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

2007 FDA drug approvals: a year of flux.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Antibiotic interactions that select against resistance.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Structure-based maximal affinity model predicts small-molecule druggability.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

ErG: 2D pharmacophore descriptions for scaffold hopping.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Emergent behavior of growing knowledge about molecular interactions.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

Classification of kinase inhibitors using a Bayesian model

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182413

26 November 2018

1 reference

12 December 2020

Target analysis: a priori assessment of druggability

1 reference

12 December 2020

Functional essentiality from topology features in metabolic networks: a case study in yeast

1 reference

12 December 2020

Essentiality is an emergent property of metabolic network wiring

1 reference

12 December 2020

10.2174/156802611795429130

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21401504%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21401504

1 reference