(Q30412189)

20 August 2017

Mechanisms of cyclic AMP compartmentation revealed by computational models (English)

1 reference

20 August 2017

Eric C Greenwald

2

0 references

author name string

Jeffrey J Saucerman

series ordinal

1

1 reference

PMC publication ID

3874575

20 August 2017

Renata Polanowska-Grabowska

series ordinal

3

1 reference

20 August 2017

1 January 2014

1 reference

The Journal of General Physiology

20 August 2017

1 reference

20 August 2017

143

1 reference

20 August 2017

1

1 reference

20 August 2017

39-48

1 reference

Can we decipher the information content contained within cyclic nucleotide signals?

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Architectural and functional roles of A kinase-anchoring proteins in cAMP microdomains.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Perspectives on: Cyclic nucleotide microdomains and signaling specificity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cyclic nucleotide compartmentalization: contributions of phosphodiesterases and ATP-binding cassette transporters.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Analysis of molecular movement reveals latticelike obstructions to diffusion in heart muscle cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Permeabilized rat cardiomyocyte response demonstrates intracellular origin of diffusion obstacles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Computational models reduce complexity and accelerate insight into cardiac signaling networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Compartmentalization of second messengers in neurons: a mathematical analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Integrin-mediated protein kinase A activation at the leading edge of migrating cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cytoplasmic cAMP concentrations in intact cardiac myocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Random walk models in biology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Compartmentation of cAMP signaling in cardiac myocytes: a computational study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cardiac beta-adrenergic signaling: from subcellular microdomains to heart failure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Aqueous diffusion pathways as a part of the ventricular cell ultrastructure.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Images in cardiovascular medicine. Himalayan T waves in the congenital long-QT syndrome.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Na/K pump-induced [Na](i) gradients in rat ventricular myocytes measured with two-photon microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Novel single chain cAMP sensors for receptor-induced signal propagation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

ACh-induced rebound stimulation of L-type Ca(2+) current in guinea-pig ventricular myocytes, mediated by Gbetagamma-dependent activation of adenylyl cyclase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Compartmentation of G protein-coupled signaling pathways in cardiac myocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Regulation and role of adenylyl cyclase isoforms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Variation of intracellular Ca2+ following Ca2+ current in heart. A theoretical study of ionic diffusion inside a cylindrical cell.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Activation of protein kinase by physiological concentrations of cyclic AMP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Probing the structure of cytoplasm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Hormonally specific expression of cardiac protein kinase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Solubility and diffusion coefficient of adenosine 3':5'-monophosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3874575

Hormonally specific phosphorylation of cardiac troponin I and activation of glycogen phosphorylase

20 June 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

A mathematical analysis of second messenger compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Protein kinase A type I and type II define distinct intracellular signaling compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Cyclic nucleotide analogs as probes of signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Modeling beta-adrenergic control of cardiac myocyte contractility in silico

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201311044

A genetically encoded, fluorescent indicator for cyclic AMP in living cells

21 January 2018

1 reference

12 December 2020

Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway

1 reference

12 December 2020

Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1

1 reference

12 December 2020

Functional compartmentation of cyclic AMP and protein kinase in heart

1 reference

12 December 2020

Identifiers

DOI

10.1085/JGP.201311044

1 reference

20 August 2017

1 reference

PMC publication ID

3874575

20 August 2017

PubMed publication ID

24378906

1 reference

PMC publication ID

3874575