(Q30423818)

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Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1.

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Europe PubMed Central

PMC publication ID

20 August 2017

Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1. (English)

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Europe PubMed Central

PMC publication ID

20 August 2017

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Michelle L. Olsen

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Michelle L Olsen

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Rene Raphemot

1

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Europe PubMed Central

PMC publication ID

20 August 2017

Rishin J Kadakia

2

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Europe PubMed Central

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20 August 2017

Sreedatta Banerjee

4

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Europe PubMed Central

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20 August 2017

Emily Days

5

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Europe PubMed Central

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20 August 2017

Stephen S Smith

6

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Europe PubMed Central

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20 August 2017

C David Weaver

7

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Europe PubMed Central

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20 August 2017

Jerod S Denton

8

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20 August 2017

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publication date

22 November 2013

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20 August 2017

Assay and Drug Development Technologies

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Europe PubMed Central

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20 August 2017

11

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20 August 2017

9-10

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Europe PubMed Central

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20 August 2017

532-543

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20 August 2017

Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine

1 reference

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High-throughput screening for small-molecule modulators of inward rectifier potassium channels

1 reference

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Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.

1 reference

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Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay

1 reference

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Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.

1 reference

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Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133

1 reference

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IonFlux: a microfluidic patch clamp system evaluated with human Ether-à-go-go related gene channel physiology and pharmacology

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Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels

1 reference

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Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel

1 reference

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Inwardly rectifying potassium channels: their structure, function, and physiological roles

1 reference

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High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.

1 reference

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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

1 reference

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Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations

1 reference

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Breathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birth

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Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10.

1 reference

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Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

1 reference

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Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel

1 reference

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The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating

1 reference

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A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors

1 reference

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Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation

1 reference

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20 June 2018

Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3870600

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Functional expression of Kir4.1 channels in spinal cord astrocytes

1 reference

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Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.

1 reference

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A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

1 reference

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An inward rectifier K(+) channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channels

1 reference

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Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina

1 reference

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Inhibition of neuronal KV potassium currents by the antidepressant drug, fluoxetine

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Block by fluoxetine of volume-regulated anion channels

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Identification of endogenous outward currents in the human embryonic kidney (HEK 293) cell line

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Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells

1 reference

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A review of the respiratory disorder in the Rett syndrome

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1 reference

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Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors

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1 reference

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1 reference

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1 reference

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Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1.

1 reference

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1 reference

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24266659

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24266659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/ADT.2013.544

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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