(Q30424185)

English

Pandemic 2009 H1N1 influenza A virus carrying a Q136K mutation in the neuraminidase gene is resistant to zanamivir but exhibits reduced fitness in the guinea pig transmission model

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Pandemic 2009 H1N1 influenza A virus carrying a Q136K mutation in the neuraminidase gene is resistant to zanamivir but exhibits reduced fitness in the guinea pig transmission model (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

pathogen transmission

0 references

0 references

1 reference

based on heuristic

inferred from title

influenza A virus

object named as

influenza A virus

1 reference

based on heuristic

inferred from title

author name string

Michael M Kaminski

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Annette Ohnemus

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Peter Staeheli

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Dennis Rubbenstroth

4

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

publication date

28 November 2012

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

number of pages

4

1 reference

based on heuristic

inferred from page(s)

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

87

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

1912-1915

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.

1 reference

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Safety, tolerability, and pharmacokinetics of intravenous oseltamivir: single- and multiple-dose phase I studies with healthy volunteers

1 reference

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In vitro passaging of a pandemic H1N1/09 virus selects for viruses with neuraminidase mutations conferring high-level resistance to oseltamivir and peramivir, but not to zanamivir

1 reference

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20 June 2018

Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives

1 reference

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20 June 2018

Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets

1 reference

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Severe H1N1-associated acute respiratory failure in immunocompromised children

1 reference

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Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors

1 reference

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20 June 2018

Characterization of oseltamivir-resistant 2009 H1N1 pandemic influenza A viruses

1 reference

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20 June 2018

Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models.

1 reference

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20 June 2018

Oseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferrets

1 reference

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Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

1 reference

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20 June 2018

Permissive secondary mutations enable the evolution of influenza oseltamivir resistance

1 reference

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20 June 2018

Use of intravenous zanamivir after development of oseltamivir resistance in a critically Ill immunosuppressed child infected with 2009 pandemic influenza A (H1N1) virus.

1 reference

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20 June 2018

Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza

1 reference

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20 June 2018

Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.

1 reference

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20 June 2018

Host cell selection of influenza neuraminidase variants: implications for drug resistance monitoring in A(H1N1) viruses

1 reference

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20 June 2018

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation

1 reference

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20 June 2018

Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

1 reference

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20 June 2018

Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

20 June 2018

Global transmission of oseltamivir-resistant influenza

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

20 June 2018

Oseltamivir-resistant influenza viruses A (H1N1), Norway, 2007-08

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

20 June 2018

Protection of chickens against H5N1 highly pathogenic avian influenza virus infection by live vaccination with infectious laryngotracheitis virus recombinants expressing H5 hemagglutinin and N1 neuraminidase

1 reference

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20 June 2018

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

20 June 2018

The war against influenza: discovery and development of sialidase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

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Antiviral agents active against influenza A viruses.

1 reference

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20 June 2018

Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro.

1 reference

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20 June 2018

Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

20 June 2018

Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

1 reference

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Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.

1 reference

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20 June 2018

The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo.

1 reference

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20 June 2018

Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.

1 reference

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20 June 2018

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

1 reference

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20 June 2018

Emergence of a multidrug-resistant pandemic influenza A (H1N1) virus

1 reference

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26 November 2018

Possible harms of oseltamivir--a call for urgent action

1 reference

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26 November 2018

Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

26 November 2018

Influenza virus carrying neuraminidase with reduced sensitivity to oseltamivir carboxylate has altered properties in vitro and is compromised for infectivity and replicative ability in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554154

26 November 2018

Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers

1 reference

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26 November 2018

Identifiers

10.1128/JVI.02507-12

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

0 references

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