(Q30430251)

13 October 2017

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells (English)

1 reference

Miguel Vicente-Manzanares

13 October 2017

series ordinal

1

1 reference

13 October 2017

Karen Newell-Litwa

2

0 references

Alan Rick Horwitz

series ordinal

5

object named as

Alan Rick Horwitz

1 reference

13 October 2017

4

Leanna A Whitmore

1 reference

13 October 2017

3

Alexia I Bachir

1 reference

PMCID

3080254

13 October 2017

language of work or name

English

0 references

publication date

11 April 2011

1 reference

13 October 2017

Journal of Cell Biology

1 reference

13 October 2017

193

1 reference

13 October 2017

381-396

1 reference

13 October 2017

2

1 reference

PMCID

3080254

describes a project that uses

13 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3080254/fullTextXML

inferred from PubMed Central ID database lookup

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

20 June 2018

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Non-muscle myosin II takes centre stage in cell adhesion and migration

20 June 2018

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20 June 2018

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20 June 2018

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Local cortical tension by myosin II guides 3D endothelial cell branching

20 June 2018

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Mechanically activated integrin switch controls alpha5beta1 function

20 June 2018

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Stretching single talin rod molecules activates vinculin binding

20 June 2018

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Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

20 June 2018

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Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

20 June 2018

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Morphogenetic cell movements: diversity from modular mechanical properties

20 June 2018

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Segregation and activation of myosin IIB creates a rear in migrating cells

20 June 2018

1 reference

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Unravelling the structure of the lamellipodium

20 June 2018

1 reference

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Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

20 June 2018

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FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

20 June 2018

1 reference

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Identification of phosphorylation sites in betaPIX and PAK1

20 June 2018

1 reference

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Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Catching a GEF by its tail

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

p130Cas: a versatile scaffold in signaling networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

The comings and goings of actin: coupling protrusion and retraction in cell motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

20 June 2018

1 reference

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Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

20 June 2018

1 reference

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Paxillin: adapting to change

20 June 2018

1 reference

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Chemotaxis: signalling the way forward

20 June 2018

1 reference

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A single class II myosin modulates T cell motility and stopping, but not synapse formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Nonmuscle myosin IIb is involved in the guidance of fibroblast migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Cell migration: integrating signals from front to back

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Cellular motility driven by assembly and disassembly of actin filaments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Cell polarity: Par6, aPKC and cytoskeletal crosstalk

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Single-molecule speckle analysis of actin filament turnover in lamellipodia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Distinct roles of frontal and rear cell-substrate adhesions in fibroblast migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Localized Rac activation dynamics visualized in living cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

A cell's sense of direction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Self-polarization and directional motility of cytoplasm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Cytoplasmic dynamics of myosin IIA and IIB: spatial 'sorting' of isoforms in locomoting cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Identification of Novel Graded Polarity Actin Filament Bundles in Locomoting Heart Fibroblasts: Implications for the Generation of Motile Force

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

A role for Rac in Tiam1-induced membrane ruffling and invasion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Differential localization of myosin-II isozymes in human cultured cells and blood cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080254

Forming the cell rear first: breaking cell symmetry to trigger directed cell migration.

20 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201012159

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201012159

A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201012159

Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201012159

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482721

12 December 2020

inferred from PubMed ID database lookup

Calyculin A and okadaic acid: inhibitors of protein phosphatase activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482721

12 December 2020

inferred from PubMed ID database lookup

Graded actin filament polarity is the organization of oriented actomyosin II filament bundles required for fibroblast polarization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482721

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.201012159

1 reference

13 October 2017

1 reference

13 October 2017

1 reference

PMCID

3080254