(Q30432710)

English

Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Increased acid stability of the hemagglutinin protein enhances H5N1 influenza virus growth in the upper respiratory tract but is insufficient for transmission in ferrets (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

pathogen transmission

0 references

object named as

Hassan Zaraket

1

0 references

Robert G. Webster

9

object named as

Robert G Webster

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

8

object named as

Richard J Webby

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

5

object named as

Sun-Woo Yoon

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

3

object named as

Susu Duan

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Rachelle Salomon

7

object named as

Rachelle Salomon

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Olga A Bridges

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Tatiana Baranovich

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Mark L Reed

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Charles J Russell

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

publication date

3 July 2013

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

87

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

9911-9922

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Influenza HA subtypes demonstrate divergent phenotypes for cleavage activation and pH of fusion: implications for host range and adaptation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus replication and pathogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Identification of novel influenza A virus proteins translated from PA mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

An overlapping protein-coding region in influenza A virus segment 3 modulates the host response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Airborne transmission of influenza A/H5N1 virus between ferrets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The role of receptor binding specificity in interspecies transmission of influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Predicting 'airborne' influenza viruses: (trans-) mission impossible?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Evolution and adaptation of hemagglutinin gene of human H5N1 influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Pause on avian flu transmission research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Inactivation of high and low pathogenic avian influenza virus H5 subtypes by copper ions incorporated in zeolite-textile materials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Acid Stability of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The cell biology of receptor-mediated virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Enhanced growth of influenza vaccine seed viruses in vero cells mediated by broadening the optimal pH range for virus membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Continued evolution of highly pathogenic avian influenza A (H5N1): updated nomenclature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The pathogenesis of influenza virus infections: the contributions of virus and host factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The first influenza pandemic of the new millennium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Molecular adaptation of an H7N3 wild duck influenza virus following experimental multiple passages in quail and turkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity and transmissibility in ducks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

H5N1 influenza viruses: outbreaks and biological properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Past, present, and possible future human infection with influenza virus A subtype H7.

1 reference

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20 June 2018

Human infection with highly pathogenic avian influenza A (H5N1) virus: review of clinical issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The influenza virus enigma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Amino acid residues in the fusion peptide pocket regulate the pH of activation of the H5N1 influenza virus hemagglutinin protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Human infection with highly pathogenic avian influenza virus (H5N1) in northern Vietnam, 2004-2005.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Experimental evolution of human influenza virus H3 hemagglutinin in the mouse lung identifies adaptive regions in HA1 and HA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Epitope mapping of the hemagglutinin molecule of a highly pathogenic H5N1 influenza virus by using monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Inefficient transmission of H5N1 influenza viruses in a ferret contact model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Contribution of H7 haemagglutinin to amantadine resistance and infectivity of influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The evolution of epidemic influenza.

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20 June 2018

Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Avian flu: influenza virus receptors in the human airway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003.

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20 June 2018

Avian influenza A (H5N1) infection in humans

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Probable person-to-person transmission of avian influenza A (H5N1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Molecular determinants within the surface proteins involved in the pathogenicity of H5N1 influenza viruses in chickens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Re-emergence of fatal human influenza A subtype H5N1 disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Rescue of influenza B virus from eight plasmids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Apoptosis by influenza viruses correlates with efficiency of viral mRNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Human infection with influenza H9N2.

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20 June 2018

Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Changes in the hemagglutinin gene of the neurovirulent influenza virus strain A/NWS/33.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Structure of influenza haemagglutinin at the pH of membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Fusion mutants of the influenza virus hemagglutinin glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Structural basis of immune recognition of influenza virus hemagglutinin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

20 June 2018

Evolution and ecology of influenza A viruses

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20 June 2018

Altered receptor specificity and fusion activity of the haemagglutinin contribute to high virulence of a mouse-adapted influenza A virus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

26 November 2018

Molecular evolution of human influenza A viruses in a local area during eight influenza epidemics from 2000 to 2007.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

26 November 2018

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin

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26 November 2018

Avian influenza H5N1 outbreaks in Romanian and Danish poultry, and large H5N1 cluster in an Indonesian family

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

26 November 2018

Distribution of intranasal instillations in mice: effects of volume, time, body position, and anesthesia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

26 November 2018

Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3754100

26 November 2018

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01175-13

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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