(Q30436035)

English

The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1 reference

based on heuristic

inferred from title

Caroline S. Hill

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

John P. Greenwood

3

object named as

John Greenwood

0 references

object named as

Maria S Balda

6

0 references

object named as

Karl Matter

5

0 references

author name string

Anna Tsapara

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Phillip Luthert

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

publication date

20 January 2010

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

21

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

860-870

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2836967/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

GEF-H1 mediates tumor necrosis factor-alpha-induced Rho activation and myosin phosphorylation: role in the regulation of tubular paracellular permeability

1 reference

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20 June 2018

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Non-Smad pathways in TGF-beta signaling

1 reference

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20 June 2018

Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target.

1 reference

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20 June 2018

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition

1 reference

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20 June 2018

Mammalian Rho GTPases: new insights into their functions from in vivo studies

1 reference

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20 June 2018

Involvement of RhoA, ROCK I and myosin II in inverted orientation of epithelial polarity

1 reference

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20 June 2018

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

1 reference

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20 June 2018

Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis

1 reference

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20 June 2018

Regulation of cell-cell adhesion by the cadherin-catenin complex

1 reference

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20 June 2018

Cadherin switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA.

1 reference

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20 June 2018

How the Smads regulate transcription

1 reference

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20 June 2018

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

1 reference

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20 June 2018

VEGF modulation of retinal pigment epithelium resistance

1 reference

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20 June 2018

Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions

1 reference

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20 June 2018

GEFs and GAPs: critical elements in the control of small G proteins

1 reference

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20 June 2018

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

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20 June 2018

Actin' together: serum response factor, its cofactors and the link to signal transduction

1 reference

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20 June 2018

Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus

1 reference

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20 June 2018

Transforming growth factor-beta1 regulates macrophage migration via RhoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Excitation-transcription coupling in arterial smooth muscle.

1 reference

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20 June 2018

RhoA signaling in phorbol ester-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Renal fibrosis: new insights into the pathogenesis and therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of rho-kinase inhibitor in hypertensive glomerulosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Epithelial cell shape and Rho small GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Rho GTPases and the control of cell behaviour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

TGF-beta and epithelial-to-mesenchymal transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836967

20 June 2018

Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition

1 reference

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20 June 2018

PAK4 mediates morphological changes through the regulation of GEF-H1

1 reference

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20 June 2018

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

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20 June 2018

Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice

1 reference

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20 June 2018

Interactively optimizing signal-to-noise ratios in expression profiling: project-specific algorithm selection and detection p-value weighting in Affymetrix microarrays.

1 reference

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p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor

1 reference

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20 June 2018

Electrical wound-healing assay for cells in vitro

1 reference

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20 June 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

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20 June 2018

A transforming growth factor-beta control element required for SM alpha-actin expression in vivo also partially mediates GKLF-dependent transcriptional repression

1 reference

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Role of Smad4 on TGF-beta-induced extracellular matrix stimulation in mesangial cells

1 reference

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20 June 2018

Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail

1 reference

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20 June 2018

Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability

1 reference

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20 June 2018

Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching

1 reference

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

1 reference

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20 June 2018

TGF-betas synthesized by RPE cells have autocrine activity on mesenchymal transformation and cell proliferation

1 reference

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

1 reference

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20 June 2018

The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation

1 reference

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

1 reference

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20 June 2018

Regulation of smooth muscle alpha-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions

1 reference

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20 June 2018

Expression of vitreous cytokines in proliferative vitreoretinopathy: a prospective study

1 reference

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20 June 2018

RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation

1 reference

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20 June 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

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Microtubules containing detyrosinated tubulin are less dynamic

1 reference

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20 June 2018

Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye

1 reference

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20 June 2018

Cytoskeleton in normal and reactive human retinal pigment epithelial cells

1 reference

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20 June 2018

GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction

1 reference

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Transforming growth factor-beta1 regulates cell growth and causes downregulation of SMemb/non-muscle myosin heavy chain B mRNA in human prostate stromal cells

1 reference

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26 November 2018

Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells.

1 reference

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26 November 2018

Involvement of rho-kinase pathway in contractile activity of rabbit RPE cells in vivo and in vitro

1 reference

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26 November 2018

Growth of cultured porcine retinal pigment epithelial cells

1 reference

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26 November 2018

p38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration.

1 reference

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In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium

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26 November 2018

Central role for Rho in TGF-beta1-induced alpha-smooth muscle actin expression during epithelial-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix and the retinal pigment epithelium in proliferative retinal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-07-0567

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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