(Q30445717)

21 June 2017

1 reference

title

Molecular mechanisms and treatment of bone metastasis (English)

1 reference

21 June 2017

2

Theresa A Guise

1 reference

21 June 2017

Gregory A Clines

1

1 reference

21 June 2017

6 March 2008

1 reference

Expert Reviews in Molecular Medicine

21 June 2017

1 reference

21 June 2017

10

1 reference

21 June 2017

e7

1 reference

Integrin activation controls metastasis in human breast cancer

21 June 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Involvement of chemokine receptors in breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Molecular mechanisms of action of bisphosphonates: current status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

New functions for the matrix metalloproteinases in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A comparison of the palliative effects of strontium-89 and external beam radiotherapy in metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Impact of IGF-I and CYP19 gene polymorphisms on the survival of patients with metastatic prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Genes associated with breast cancer metastatic to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Anastrozole (Arimidex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Prospective evaluation of the peptide-bound collagen type I cross-links N-telopeptide and C-telopeptide in predicting bone metastases status

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Efficacy of multidetector row computed tomography of the spine in patients with multiple myeloma: comparison with magnetic resonance imaging and fluorodeoxyglucose-positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Fusion of metabolic function and morphology: sequential [18F]fluorodeoxyglucose positron-emission tomography/computed tomography studies yield new insights into the natural history of bone metastases in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Diagnostic evaluation of low back pain with emphasis on imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Cancer as a cause of back pain: frequency, clinical presentation, and diagnostic strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Endothelin and the tumorigenic component of bone cancer pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Biology of bone cancer pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Does PSA play a role as a promoting agent during the initiation and/or progression of prostate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A N-terminal PTHrP peptide fragment void of a PTH/PTHrP-receptor binding domain activates cardiac ET(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Mechanisms of bone metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Metastasis to bone: causes, consequences and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Extracellular calcium-sensing receptor expression and its potential role in regulating parathyroid hormone-related peptide secretion in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

The IGF system and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Proteomic profiling of primary breast cancer predicts axillary lymph node metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A pooled analysis of bone marrow micrometastasis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Endothelin receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Bisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

Prostate cancer cells promote osteoblastic bone metastases through Wnts

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Plasma MMP-9 (92 kDa-MMP) activity is useful in the follow-up and in the assessment of prognosis in breast cancer patients

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Samarium Sm-153 lexidronam for the palliation of bone pain associated with metastases

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

The detection and isolation of viable prostate-specific antigen positive epithelial cells by enrichment: a comparison to standard prostate-specific antigen reverse transcriptase polymerase chain reaction and its clinical relevance in prostate cancer

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen or Arimidex Randomized Group Efficacy and Tolerability study

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Meta-analysis of trials comparing toremifene with tamoxifen and factors predicting outcome of antiestrogen therapy in postmenopausal women with breast cancer

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Mitogenic response of osteoblast cells to prostate-specific antigen suggests an activation of latent TGF-beta and a proteolytic modulation of cell adhesion receptors

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Breast cancer cells interact with osteoblasts to support osteoclast formation

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

The management of pathological fractures

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Calcium stimulates parathyroid hormone-related protein production in Leydig tumor cells through a putative cation-sensing mechanism

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Suppression of prostate cancer induced bone remodeling by the endothelin receptor A antagonist atrasentan

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

The molecular pathogenesis of Paget disease of bone.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Vertebroplasty and kyphoplasty in the treatment of malignant vertebral fractures

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Accuracy of fluorodeoxyglucose-positron emission tomography for diagnosis of single bone metastasis: comparison with bone scintigraphy.

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials

1 reference

https://api.crossref.org/works/10.1017%2FS1462399408000616

7 January 2021

10.1017/S1462399408000616

Identifiers

DOI

1 reference

21 June 2017

1 reference

PubMed ID

18321396