(Q30459096)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Metabolic side-effects of the novel second-generation antipsychotic drugs asenapine and iloperidone: a comparison with olanzapine (English)

1 reference

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22 February 2020

2

1 reference

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22 February 2020

William G. Honer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Alasdair M Barr

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1

Heidi N Boyda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

4

Erin Hawkes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Catherine C Y Pang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Daniel Wong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Chen Helen Jin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

9 January 2013

1 reference

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22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

1

1 reference

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22 February 2020

page(s)

e53459

1 reference

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Creative Commons Attribution 4.0 International

22 February 2020

copyright license

start time

9 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Recent advances in understanding and mitigating adipogenic and metabolic effects of antipsychotic drugs

1 reference

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Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats.

14 July 2018

1 reference

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Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system.

14 July 2018

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Safety and tolerability of antipsychotic polypharmacy

14 July 2018

1 reference

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Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain

14 July 2018

1 reference

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A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.

14 July 2018

1 reference

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Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat.

14 July 2018

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Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics

14 July 2018

1 reference

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Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-analysis

14 July 2018

1 reference

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Central Nervous System Delivery of the Antipsychotic Olanzapine Induces Hepatic Insulin Resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Preclinical models of antipsychotic drug-induced metabolic side effects.

14 July 2018

1 reference

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Effect of antipsychotic medications on glucose and lipid levels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Persistent antipsychotic polypharmacy and excessive dosing in the community psychiatric treatment setting: a review of medication profiles in 435 Canadian outpatients.

14 July 2018

1 reference

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Are weight gain and metabolic side effects of atypical antipsychotics dose dependent? A literature review

14 July 2018

1 reference

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Asenapine effects in animal models of psychosis and cognitive function

14 July 2018

1 reference

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Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat.

14 July 2018

1 reference

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Pharmacological management of atypical antipsychotic-induced weight gain.

14 July 2018

1 reference

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Managing weight gain and metabolic issues in patients treated with atypical antipsychotics.

14 July 2018

1 reference

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Long-term efficacy and safety of iloperidone: results from 3 clinical trials for the treatment of schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

14 July 2018

1 reference

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Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment

14 July 2018

1 reference

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Effects of olanzapine and ziprasidone on glucose tolerance in healthy volunteers

14 July 2018

1 reference

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Antipsychotic medications: metabolic and cardiovascular risk

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents

14 July 2018

1 reference

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Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review

14 July 2018

2 references

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14 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Evaluation of insulin sensitivity in clinical practice and in research settings

21 January 2018

1 reference

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Abnormalities in glucose regulation during antipsychotic treatment of schizophrenia

14 July 2018

1 reference

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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

14 July 2018

1 reference

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3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873).

14 July 2018

1 reference

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Rosiglitazone in the assistance of metabolic control during olanzapine administration in schizophrenia: a pilot double-blind, placebo-controlled, 12-week trial

14 July 2018

1 reference

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Extended release metformin for metabolic control assistance during prolonged clozapine administration: a 14 week, double-blind, parallel group, placebo-controlled study.

21 January 2018

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Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial

21 January 2018

1 reference

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Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Effects of olanzapine and haloperidol on the metabolic status of healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

A parametric study of the acute effects of antipsychotic drugs on glucose sensitivity in an animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Comparative effects of the antipsychotics sulpiride or risperidone in rats. I: bodyweight, food intake, body composition, hormones and glucose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Sensitivity of the female rat to olanzapine-induced weight gain--far from the clinic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Intermittent treatment with olanzapine causes sensitization of the metabolic side-effects in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Heterozygous reeler mice exhibit alterations in sensorimotor gating but not presynaptic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Abnormalities of presynaptic protein CDCrel-1 in striatum of rats reared in social isolation: relevance to neural connectivity in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Surrogate measures of insulin resistance: of rats, mice, and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Insulin resistance and decreased glucose-stimulated insulin secretion after acute olanzapine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Early perturbation in feeding behaviour and energy homeostasy in olanzapine-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

A parametric analysis of olanzapine-induced weight gain in female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Elevation of systolic blood pressure in an animal model of olanzapine induced weight gain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Asenapine versus olanzapine in people with persistent negative symptoms of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Efficacy and safety of asenapine in a placebo- and haloperidol-controlled trial in patients with acute exacerbation of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

A comparison of antipsychotic drug-defined daily doses versus chlorpromazine equivalent doses in patients with or without extrapyramidal motor symptoms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Self-reported motivation to smoke in schizophrenia is related to antipsychotic drug treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Excessive antipsychotic dosing in a Canadian outpatient population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

A double-blind, randomized trial to evaluate the pharmacokinetics and tolerability of 30 or 40 mg/d oral olanzapine relative to 20 mg/d oral olanzapine in stable psychiatric subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053459

Short-term safety and pharmacokinetic profile of asenapine in older patients with psychosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541274

Schizophrenia patients at higher risk of diabetes, hypertension and hyperlipidemia: a population-based study

26 November 2018

1 reference

12 December 2020

Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model

1 reference

12 December 2020

Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects

1 reference

12 December 2020

Olanzapine effects on body composition, food preference, glucose metabolism and insulin sensitivity in the rat

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0053459

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23326434

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23326434%20AND%20SRC:MED&resulttype=core&format=json