(Q30467288)

English

Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Huntington's disease

0 references

1 reference

based on heuristic

inferred from title

author name string

Randi-Michelle Cowin

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Nghiem Bui

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Deanna Graham

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jennie R Green

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lisa A Yuva-Paylor

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Andreas Weiss

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Richard Paylor

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 June 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Mammalian Genome

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

5-6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

367-377

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Huntingtin-associated protein-1 is a modifier of the age-at-onset of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

The S18Y polymorphism in the UCHL1 gene is a genetic modifier in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Genetic mapping and ENU mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Family and molecular data for a fine analysis of age at onset in Huntington disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Familial aggregation of psychotic symptoms in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Mouse ENU mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Familial psychiatric presentation of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Trinucleotide repeat length instability and age of onset in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Characterization of benzodiazepine-sensitive behaviors in the A/J and C57BL/6J inbred strains of mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Injections of atropine into the caudate nucleus impair the acquisition and the maintenance of passive avoidance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Thigmotaxis as a test for anxiolytic activity in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Heterosis and resistance to DFP effects on spatial learning in C57BL X DBA hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

20 June 2018

Inbred mouse strain differences in the establishment of long-term fear memory

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Habituation of activity in an open field: A survey of inbred strains and F1 hybrids.

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Assessment of locomotor activity, acoustic and tactile startle, and prepulse inhibition of startle in inbred mouse strains and F1 hybrids: implications of genetic background for single gene and quantitative trait loci analyses.

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Time-dependent deficits of rat's memory consolidation induced by tetrodotoxin injections into the caudate-putamen, nucleus accumbens, and globus pallidus.

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Genetic analysis of candidate genes modifying the age-at-onset in Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Familial influence on age of onset among siblings with Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

PGC-1alpha as modifier of onset age in Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS00335-012-9391-5

21 January 2018

Familial aggregation of schizophrenia-like symptoms in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357469

26 November 2018

Identifiers

10.1007/S00335-012-9391-5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q30467288&oldid=2194876192"