(Q30480454)

12 August 2017

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front (English)

1 reference

12 August 2017

Zachary A Knight

3

0 references

author name string

Alexandra Van Keymeulen

1

1 reference

12 August 2017

Kit Wong

2

1 reference

12 August 2017

Cedric Govaerts

4

1 reference

12 August 2017

Klaus M Hahn

5

1 reference

12 August 2017

Kevan M Shokat

6

1 reference

12 August 2017

Henry R Bourne

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

24 July 2006

1 reference

12 August 2017

9

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

12 August 2017

174

1 reference

12 August 2017

437-445

1 reference

12 August 2017

3

1 reference

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Spatiotemporal dynamics of RhoA activity in migrating cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

A microtubule-dependent zone of active RhoA during cleavage plane specification

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Neutrophil microtubules suppress polarity and enhance directional migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Regulation of PTEN by Rho small GTPases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Concentric zones of active RhoA and Cdc42 around single cell wounds

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Biology of the p21-activated kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Eukaryotic chemotaxis: distinctions between directional sensing and polarization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cellular control of actin nucleation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cell motility: can Rho GTPases and microtubules point the way?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Localized Rac activation dynamics visualized in living cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Ras family GTPases control growth of astrocyte processes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

p110δ, a novel phosphoinositide 3-kinase in leukocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa

14 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Centrosome localization determines neuronal polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

PTEN regulates motility but not directionality during leukocyte chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Regulation of breast cancer cell chemotaxis by the phosphoinositide 3-kinase p110delta.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Microtubule capture: IQGAP and CLIP-170 expand the repertoire

26 November 2018

1 reference

12 December 2020

Orientation of chemotactic cells and growth cones: models and mechanisms

1 reference

12 December 2020

A membrane-permeant ester of phosphatidylinositol 3,4, 5-trisphosphate (PIP(3)) is an activator of human neutrophil migration

1 reference

12 December 2020

Stimulation of human neutrophils by chemotactic factors is associated with the activation of phosphatidylinositol 3-kinase gamma

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200604113

1 reference

12 August 2017

1 reference

12 August 2017

1 reference