(Q30486309)

18 August 2017

Ligand-induced global transitions in the catalytic domain of protein kinase A. (English)

1 reference

18 August 2017

1

1 reference

18 August 2017

4

José N Onuchic

1 reference

18 August 2017

Patricia A Jennings

2

1 reference

18 August 2017

Joseph A Adams

series ordinal

3

1 reference

18 August 2017

language of work or name

English

0 references

publication date

9 February 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

106

1 reference

18 August 2017

9

1 reference

18 August 2017

3023-3028

1 reference

Structural basis for the recognition of c-Src by its inactivator Csk

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Src kinase conformational activation: thermodynamics, pathways, and mechanisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Illuminating the mechanistic roles of enzyme conformational dynamics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Mechanical control of the directional stepping dynamics of the kinesin motor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

On the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Internal strain regulates the nucleotide binding site of the kinesin leading head

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Conformational transitions of adenylate kinase: switching by cracking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Dynamics of allosteric transitions in GroEL.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Exploring biomolecular machines: energy landscape control of biological reactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Molecular dynamics of apo-adenylate kinase: a principal component analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Application of a Theory of Enzyme Specificity to Protein Synthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Large amplitude conformational change in proteins explored with a plastic network model: adenylate kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

RNA and protein folding: common themes and variations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

2.0 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Probing protein structure by limited proteolysis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

The protein folding 'speed limit'.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

PKA: a portrait of protein kinase dynamics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Dynamics of cAMP-dependent protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Structural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Signal transduction: hanging on a scaffold.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Participation of ADP dissociation in the rate-determining step in cAMP-dependent protein kinase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Theory of protein folding: the energy landscape perspective

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Insights into biomolecular function from small-angle scattering.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

The phosphorylase b to a converting enzyme of rabbit skeletal muscle.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

A template for the protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

A Src-like inactive conformation in the abl tyrosine kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Release of ADP from the catalytic subunit of protein kinase A: a molecular dynamics simulation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Allosteric communication in dihydrofolate reductase: signaling network and pathways for closed to occluded transition and back

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

cAMP activation of PKA defines an ancient signaling mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Chemotaxis in Escherichia coli: a molecular model for robust precise adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Gaussian Dynamics of Folded Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Protein Conformational Transitions: The Closure Mechanism of a Kinase Explored by Atomistic Simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

High resolution, high-throughput amide deuterium exchange-mass spectrometry (DXMS) determination of protein binding site structure and dynamics: utility in pharmaceutical design.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651249

Nature of Forces between Large Molecules of Biological Interest*

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813266106

Protein dynamics from NMR

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19204278

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Network of dynamically important residues in the open/closed transition in polymerases is strongly conserved

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19204278

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0813266106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

19204278

1 reference