(Q30486818)

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Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction

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scholarly article

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Europe PubMed Central

PMC publication ID

18 August 2017

Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

dendritic spine

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inferred from title

Richard J Weinberg

object named as

Richard Weinberg

4

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author name string

Jubin Ryu

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kensuke Futai

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Monica Feliu

3

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Europe PubMed Central

PMC publication ID

18 August 2017

Morgan Sheng

5

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Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

1 August 2008

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Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

18 August 2017

28

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Europe PubMed Central

PMC publication ID

18 August 2017

33

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

8178-8188

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity

1 reference

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20 June 2018

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

1 reference

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20 June 2018

Alpha3-integrins are required for hippocampal long-term potentiation and working memory.

1 reference

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20 June 2018

N-cadherin regulates cytoskeletally associated IQGAP1/ERK signaling and memory formation

1 reference

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20 June 2018

A hippocampal Cdk5 pathway regulates extinction of contextual fear

1 reference

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20 June 2018

The postsynaptic architecture of excitatory synapses: a more quantitative view

1 reference

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20 June 2018

Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert

1 reference

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20 June 2018

alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons

1 reference

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20 June 2018

Mechanisms of fear extinction

1 reference

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20 June 2018

Hippocampal Mek/Erk signaling mediates extinction of contextual freezing behavior

1 reference

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20 June 2018

Fear extinction in rats: implications for human brain imaging and anxiety disorders

1 reference

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Emotional learning and glutamate: translational perspectives

1 reference

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20 June 2018

Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory

1 reference

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20 June 2018

Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder

1 reference

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20 June 2018

Rap2-JNK removes synaptic AMPA receptors during depotentiation

1 reference

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20 June 2018

Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking

1 reference

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20 June 2018

Linking Rap to cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton

1 reference

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20 June 2018

Identification and verification of novel rodent postsynaptic density proteins

1 reference

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20 June 2018

Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry

1 reference

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20 June 2018

Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Integrin requirement for hippocampal synaptic plasticity and spatial memory

1 reference

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20 June 2018

Behavioral and neural analysis of extinction

1 reference

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20 June 2018

Neurons in medial prefrontal cortex signal memory for fear extinction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Multicolor "DiOlistic" labeling of the nervous system using lipophilic dye combinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

1 reference

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20 June 2018

A necessity for MAP kinase activation in mammalian spatial learning.

1 reference

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20 June 2018

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

1 reference

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20 June 2018

Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665130

20 June 2018

A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation.

1 reference

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20 June 2018

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

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20 June 2018

Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation.

1 reference

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20 June 2018

Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation

1 reference

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20 June 2018

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

1 reference

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20 June 2018

ralGDS family members interact with the effector loop of ras p21.

1 reference

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20 June 2018

Place navigation impaired in rats with hippocampal lesions

1 reference

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Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

1 reference

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20 June 2018

Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region

1 reference

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20 June 2018

A ras-related gene with transformation suppressor activity

1 reference

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An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

1 reference

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A domain responsible for the transformation suppressor activity in Krev-1 protein

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The product of the rap2 gene, member of the ras superfamily. Biochemical characterization and site-directed mutagenesis

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20 June 2018

Differential roles of Rap1 and Rap2 small GTPases in neurite retraction and synapse elimination in hippocampal spiny neurons

1 reference

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26 November 2018

Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins.

1 reference

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26 November 2018

Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation.

1 reference

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Integrins control dendritic spine plasticity in hippocampal neurons through NMDA receptor and Ca2+/calmodulin-dependent protein kinase II-mediated actin reorganization.

1 reference

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Delayed recall of fear extinction in rats with lesions of ventral medial prefrontal cortex.

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Distinct roles of hippocampal de novo protein synthesis and actin rearrangement in extinction of contextual fear.

1 reference

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Selective modification of short-term hippocampal synaptic plasticity and impaired memory extinction in mice with a congenitally reduced hippocampal commissure

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A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory.

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Subtle neurologic compromise as a vulnerability factor for combat-related posttraumatic stress disorder: results of a twin study

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Identifiers

10.1523/JNEUROSCI.1944-08.2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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