(Q24302294)

RAP2A, member of RAS oncogene family

GOA release 2020-03-11

1 reference

protein autophosphorylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Kiyohito Taira

1

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Masato Umikawa

2

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Kimiko Takei

3

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Bat-Erdene Myagmar

4

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Manabu Shinzato

5

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Noriko Machida

6

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Hiroshi Uezato

7

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Shigeo Nonaka

8

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Ken-ichi Kariya

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

19 November 2004

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published in

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volume

279

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page(s)

49488-96

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issue

47

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cites work

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Regulation of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The effector interactions of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Effects of the ras-related rap2 protein on cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Role of the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Identification of a specific effector of the small GTP-binding protein Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Tumor necrosis factor receptor-associated factors (TRAFs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The Nck family of adapter proteins: regulators of actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

A novel partner for the GTP-bound forms of rho and rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The Ste20 group kinases as regulators of MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Signaling by the germinal center kinase family of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Mitogen-activated protein kinase kinase kinase kinase 4 as a putative effector of Rap2 to activate the c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Actin-based motility: from molecules to movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Nrk: a murine X-linked NIK (Nck-interacting kinase)-related kinase gene expressed in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Association of Frabin with the Actin Cytoskeleton Is Essential for Microspike Formation through Activation of Cdc42 Small G Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200

Role of Raf-1 conserved region 2 in regulation of Ras-dependent Raf-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406370200