(Q30491939)

English

Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera from Subjects Dosed with the Anti-C1s Monoclonal Antibody TNT009 - Results from a Randomized First-in-Human Phase 1 Trial.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28926521%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera From Subjects Dosed With the Anti-C1s Monoclonal Antibody TNT009-Results from a Randomized First-in-Human Phase 1 Trial (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28926521%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

phase I clinical trial

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Markus Wahrmann

3

1 reference

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30 March 2020

Farsad Eskandary

5

1 reference

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30 March 2020

Christian Schoergenhofer

6

1 reference

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30 March 2020

2

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Bernd Jilma

1 reference

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30 March 2020

Michael Schwameis

7

object named as

Michael Schwameis

1 reference

Europe PubMed Central

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30 March 2020

Georg A Böhmig

11

object named as

Georg A Böhmig

1 reference

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30 March 2020

author name string

Jakob Mühlbacher

1

1 reference

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30 March 2020

Johann Bartko

4

1 reference

Europe PubMed Central

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30 March 2020

Graham C Parry

8

1 reference

Europe PubMed Central

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30 March 2020

James C Gilbert

9

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30 March 2020

Sandip Panicker

10

1 reference

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30 March 2020

language of work or name

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publication date

1 October 2017

1 reference

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30 March 2020

Transplantation

1 reference

Europe PubMed Central

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30 March 2020

101

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30 March 2020

2410-2418

1 reference

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30 March 2020

10

1 reference

Europe PubMed Central

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30 March 2020

Combined integrated protocol/basket trial design for a first-in-human trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Deceased donor kidney transplantation across donor-specific antibody barriers: predictors of antibody-mediated rejection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Diagnostic Contribution of Donor-Specific Antibody Characteristics to Uncover Late Silent Antibody-Mediated Rejection-Results of a Cross-Sectional Screening Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Potential Roles for C1 Inhibitor in Transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Complement inhibition as potential new therapy for antibody-mediated rejection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Capillary C4d and Kidney Allograft Outcome in Relation to Morphologic Lesions Suggestive of Antibody-Mediated Rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

The molecular landscape of antibody-mediated kidney transplant rejection: evidence for NK involvement through CD16a Fc receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Positive crossmatch kidney transplant recipients treated with eculizumab: outcomes beyond 1 year.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

A phase I/II placebo-controlled trial of C1-inhibitor for prevention of antibody-mediated rejection in HLA sensitized patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Eculizumab and Splenectomy as Salvage Therapy for Severe Antibody-Mediated Rejection After HLA–Incompatible Kidney Transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Quantifying the risk of incompatible kidney transplantation: a multicenter study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

A systematic review of the role of C4d in the diagnosis of acute antibody-mediated rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Diagnosis and management of antibody-mediated rejection: current status and novel approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Mechanisms of rejection: role of complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Complement-binding anti-HLA antibodies and kidney-allograft survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Five-year outcomes in living donor kidney transplants with a positive crossmatch.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

The role of complement in antibody-mediated rejection in kidney transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Complement in the immunopathogenesis of rheumatic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5610566

26 November 2018

C1 Inhibitor in Acute Antibody-Mediated Rejection Nonresponsive to Conventional Therapy in Kidney Transplant Recipients: A Pilot Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28926521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/28926521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma-Derived C1 Esterase Inhibitor for Acute Antibody-Mediated Rejection Following Kidney Transplantation: Results of a Randomized Double-Blind Placebo-Controlled Pilot Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28926521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence

1 reference

https://pubmed.ncbi.nlm.nih.gov/28926521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/TP.0000000000001804

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28926521%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28926521%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

2 references

Europe PubMed Central

22 June 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28926521%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

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