(Q30493233)

19 October 2017

Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences (English)

1 reference

19 October 2017

1 reference

Daniel Menendez

1

1 reference

19 October 2017

Alberto Inga

series ordinal

2

1 reference

19 October 2017

Michael A Resnick

series ordinal

3

1 reference

19 October 2017

language of work or name

English

0 references

publication date

4 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2017

1 reference

19 October 2017

107

1 reference

19 October 2017

4

1 reference

19 October 2017

1500-1505

1 reference

The expanding universe of p53 targets

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Blinded by the Light: The Growing Complexity of p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Characterization of genome-wide p53-binding sites upon stress response.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Transcriptional control of human p53-regulated genes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Structural biology of the tumor suppressor p53.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Mechanisms of regulatory diversity within the p53 transcriptional network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional evolution of the p53 regulatory network through its target response elements

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Interactions of mutant p53 with DNA: guilt by association

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The versatile interactions of p53 with DNA: when flexibility serves specificity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

A global map of p53 transcription-factor binding sites in the human genome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Transcriptional repression by p53 through direct binding to a novel DNA element

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Definition of a consensus binding site for p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824383

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Structural basis of DNA recognition by p53 tetramers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

p53 domains: identification and characterization of two autonomous DNA-binding regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Cooperative binding of tetrameric p53 to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909129107

Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen receptor protects p53 from deactivation by human double minute-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CA/TG sequence at the 5' end of oligo(A)-tracts strongly modulates DNA curvature

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0909129107

1 reference

19 October 2017

0 references

1 reference

19 October 2017

1 reference