(Q30495530)

English

Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice

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scholarly article

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Europe PubMed Central

PMC publication ID

19 October 2017

Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

1 reference

based on heuristic

inferred from title

Kerry J. Ressler

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

author name string

Scott A Heldt

1

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

language of work or name

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publication date

1 May 2010

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Europe PubMed Central

PMC publication ID

19 October 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

30

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

21

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

7139-7151

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors

1 reference

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The effects of intra-cerebral drug infusions on animals' unconditioned fear reactions: a systematic review.

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Training-induced changes in the expression of GABAA-associated genes in the amygdala after the acquisition and extinction of Pavlovian fear

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Vagaries of conditional gene targeting

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20 June 2018

GABAA receptors: subtypes, regional distribution, and function.

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20 June 2018

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

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20 June 2018

Structure, pharmacology, and function of GABAA receptor subtypes.

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20 June 2018

GABA(A) receptor diversity and pharmacology

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20 June 2018

Localized injections of midazolam into the amygdala and hippocampus induce differential changes in anxiolytic-like motor activity in mice

1 reference

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20 June 2018

Memory effects of benzodiazepines: memory stages and types versus binding-site subtypes

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20 June 2018

The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents

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20 June 2018

Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives: zaleplon, zolpidem and zopiclone

1 reference

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20 June 2018

Modulation of rhythmic brain activity by diazepam: GABA(A) receptor subtype and state specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

1 reference

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20 June 2018

Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Compartmentation of alpha 1 and alpha 2 GABA(A) receptor subunits within rat extended amygdala: implications for benzodiazepine action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Regulation of synaptic plasticity genes during consolidation of fear conditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Subunit composition, distribution and function of GABA(A) receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Do preclinical seizure models preselect certain adverse effects of antiepileptic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

A new benzodiazepine pharmacology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Type A gamma-aminobutyric acid (GABAA) receptor subunits and benzodiazepine binding: significance to clinical syndromes and their treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Role of amygdaloid nuclei in the anxiolytic effects of benzodiazepines in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Mechanism of action of the hypnotic zolpidem in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Structure and subunit composition of GABA(A) receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Ligands for the benzodiazepine binding site--a survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Effects of centrally administered anxiolytic compounds in animal models of anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes

1 reference

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20 June 2018

Pharmacology of recombinant gamma-aminobutyric acidA receptors rendered diazepam-insensitive by point-mutated alpha-subunits.

1 reference

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20 June 2018

International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Anxiety, defence and the elevated plus-maze

1 reference

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L-NAME inhibits pentylenetetrazole and strychnine-induced seizures in mice

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20 June 2018

Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

A review of the validity and variability of the elevated plus-maze as an animal model of anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Which GABAA-receptor subtypes really occur in the brain?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

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Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors

1 reference

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20 June 2018

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

1 reference

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Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?

1 reference

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20 June 2018

Stoichiometry of a recombinant GABAA receptor deduced from mutation-induced rectification

1 reference

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20 June 2018

Evidence that the anticonflict effect of midazolam in amygdala is mediated by the specific benzodiazepine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

20 June 2018

Evidence that the amygdala is involved in benzodiazepine and serotonergic effects on punished responding but not on discrimination

1 reference

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20 June 2018

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

1 reference

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20 June 2018

Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects

1 reference

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1 reference

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20 June 2018

Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology.

1 reference

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GABA A receptor subtypes: from pharmacology to molecular biology

1 reference

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1 reference

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20 June 2018

Anxiogenic effects of the intraamygdala injection of flumazenil, a benzodiazepine receptor antagonist

1 reference

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1 reference

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Construction of cell-type specific promoter lentiviruses for optically guiding electrophysiological recordings and for targeted gene delivery

1 reference

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Cortical glutamatergic neurons mediate the motor sedative action of diazepam.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Reorganization of GABAergic circuits maintains GABAA receptor-mediated transmission onto CA1 interneurons in alpha1-subunit-null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Production and purification of lentiviral vectors

1 reference

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Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of alpha1-subunit-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Mice lacking the major adult GABAA receptor subtype have normal number of synapses, but retain juvenile IPSC kinetics until adulthood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Functional mapping of GABA A receptor subtypes in the amygdala

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

GABA(A) receptor alpha1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Resolving differences in GABAA receptor mutant mouse studies.

1 reference

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26 November 2018

Molecular and neuronal substrate for the selective attenuation of anxiety.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

Regional and age specific effects of zolpidem microinfusions in the substantia nigra on seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

The use of the rat elevated plus-maze to discriminate between non-selective and BZ-1 (omega 1) selective, benzodiazepine receptor ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905594

26 November 2018

An update on GABAA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20505082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and regional regulation of alpha1, beta2 and beta3, but not alpha2, alpha4, alpha5, alpha6, beta1 or gamma2 GABA(A) receptor subunit messenger RNAs following one-week oral flurazepam administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20505082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of chlordiazepoxide blocked by injection of GABAA and benzodiazepine receptor antagonists in the region of the anterior basolateral amygdala of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20505082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and culture of adult rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20505082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0693-10.2010

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

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