(Q30498021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Lijun Jia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jeremy S Bickel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jiaxue Wu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Meredith A Morgan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hua Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jie Yang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Xiaochun Yu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Yi Sun

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

29 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

number of pages

8

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

3379-3386

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

17 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3030344/fullTextXML

inferred from PubMed Central ID database lookup

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Structural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability

20 June 2018

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20 June 2018

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ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.

20 June 2018

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20 June 2018

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

20 June 2018

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RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27

20 June 2018

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Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress

20 June 2018

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Identification of SCF ubiquitin ligase substrates by global protein stability profiling

20 June 2018

1 reference

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ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans

20 June 2018

1 reference

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Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2.

20 June 2018

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Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.

20 June 2018

1 reference

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Cdt1 and Geminin in cancer: markers or triggers of malignant transformation?

20 June 2018

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Cancer proliferation gene discovery through functional genomics.

20 June 2018

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DNA damage signalling guards against activated oncogenes and tumour progression

20 June 2018

1 reference

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Mechanisms to control rereplication and implications for cancer

20 June 2018

1 reference

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Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior

20 June 2018

1 reference

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Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells

20 June 2018

1 reference

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A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

20 June 2018

1 reference

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20 June 2018

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Ubiquitin ligases: cell-cycle control and cancer

20 June 2018

1 reference

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Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

20 June 2018

1 reference

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An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage

20 June 2018

1 reference

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ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

20 June 2018

1 reference

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Function and regulation of cullin-RING ubiquitin ligases

20 June 2018

1 reference

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20 June 2018

1 reference

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Methods for analyzing checkpoint responses in Caenorhabditis elegans

20 June 2018

1 reference

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The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

20 June 2018

1 reference

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Genome-wide RNAi screening in Caenorhabditis elegans

20 June 2018

1 reference

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Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase

20 June 2018

1 reference

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

20 June 2018

1 reference

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Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

20 June 2018

1 reference

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The origin recognition complex: from simple origins to complex functions

20 June 2018

1 reference

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Essential role of human CDT1 in DNA replication and chromatin licensing

20 June 2018

1 reference

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Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3030344

Analysis of RING finger genes required for embryogenesis in C. elegans.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

The SCF FSN-1 ubiquitin ligase controls germline apoptosis through CEP-1/p53 in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

Polyploid tissues in the nematode Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

Chaotic license for genetic instability and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188425

SnapShot: F Box Proteins II

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115485

12 December 2020

inferred from PubMed ID database lookup

Association with cullin partners protects ROC proteins from proteasome-dependent degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115485

12 December 2020

inferred from PubMed ID database lookup

Caenorhabditis elegans RBX1 is essential for meiosis, mitotic chromosomal condensation and segregation, and cytokinesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21115485

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M110.188425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115485%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference