(Q30498100)

English

Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue

scientific article published on 21 December 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

7

object named as

Tamas Bartfai

0 references

object named as

John R Hadcock

6

0 references

object named as

Olivia Osborn

1

0 references

Manuel Sanchez-Alavez

object named as

Manuel Sanchez-Alavez

2

0 references

author name string

Jeffrey S Dubins

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Alejandro Sanchez Gonzalez

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Brad Morrison

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

publication date

21 December 2010

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

53

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

311-319

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

The novel association of the chemokine CCL22 with abdominal aortic aneurysm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Endogenous activation of spinal 5-hydroxytryptamine (5-HT) receptors contributes to the thermoregulatory activation of brown adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

The chemokine receptor CCR4 is expressed and associated with a poor prognosis in patients with gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Potent CCR4 antagonists: synthesis, evaluation, and docking study of 2,4-diaminoquinazolines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Discovery of potent CCR4 antagonists: Synthesis and structure-activity relationship study of 2,4-diaminoquinazolines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Central control of thermogenesis in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Unexpected evidence for active brown adipose tissue in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

CCR4 as a novel molecular target for immunotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

RANKL-induced CCL22/macrophage-derived chemokine produced from osteoclasts potentially promotes the bone metastasis of lung cancer expressing its receptor CCR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Endothelin-1 as a central mediator of LPS-induced fever in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Cytokines and fever

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Regulation of chemokine receptor expression in human microglia and astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Regulation of macrophage-derived chemokine (MDC, CCL22) production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Invited review: cytokine regulation of fever: studies using gene knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Cytokines and chemoattractants in allergic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Chemokine receptors: multifaceted therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Production of MDC/CCL22 by human intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Fever induction pathways: evidence from responses to systemic or local cytokine formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Inflammation and cancer: back to Virchow?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Prostaglandin E2 up-regulates macrophage-derived chemokine production but suppresses IFN-inducible protein-10 production by APC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Role of the preoptic-anterior hypothalamus in thermoregulation and fever

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Macrophage-derived chemokine (MDC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

RANTES: a new prostaglandin dependent endogenous pyrogen in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Chemokine and chemokine receptor mRNA expression in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Macrophage inflammatory protein-1: a prostaglandin-independent endogenous pyrogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Hypothalamic indomethacin fails to block fever induced in rats by central macrophage inflammatory protein-1 (MIP-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

28 July 2018

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Antagonists of CCR4 as immunomodulatory agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Activation of phosphoinositide 3-kinases by the CCR4 ligand macrophage-derived chemokine is a dispensable signal for T lymphocyte chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Accumulation of CCR4-expressing CD4+ T cells and high concentration of its ligands (TARC and MDC) in bronchoalveolar lavage fluid of patients with eosinophilic pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Involvement of CRH in fever induced by a distinct pre-formed pyrogenic factor (PFPF).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Fever induced by macrophage inflammatory protein-1 (MIP-1) in rats: Hypothalamic sites of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033975

26 November 2018

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CCL22 (MDC) for the recruitment of eosinophils during allergic pleurisy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central actions of interleukin-8 in the rat are independent of prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-derived chemokine is localized to thymic medullary epithelial cells and is a chemoattractant for CD3(+), CD4(+), CD8(low) thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of CCR4 antagonists: side-chain exploration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of chemokine receptors in insulin-resistant human skeletal muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small molecule antagonists of the CC chemokine receptor 4 (CCR4)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21177120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CYTO.2010.11.017

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

0 references

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