(Q30502199)

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Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21631939%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21631939%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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7

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2 February 2020

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Jianxin Yang

1

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2 February 2020

Margit L MacDougall

2

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2 February 2020

Michael T McDowell

3

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2 February 2020

Li Xi

4

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2 February 2020

Ru Wei

5

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2 February 2020

William J Zavadoski

6

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2 February 2020

John D Baker

8

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2 February 2020

Max Kuhn

9

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2 February 2020

Over Cabrera

10

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2 February 2020

Judith L Treadway

11

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2 February 2020

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1 June 2011

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2 February 2020

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2 February 2020

12

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2 February 2020

281

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2 February 2020

copyright license

Creative Commons Attribution 2.0 Generic

1 June 2011

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April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

https://scigraph.springernature.com/pub.10.1186/1471-2164-12-281

0 references

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Fully human monoclonal antibodies antagonizing the glucagon receptor improve glucose homeostasis in mice and monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Role of bile acids and bile acid receptors in metabolic regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

The glucagon receptor is required for the adaptive metabolic response to fasting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Transcriptional regulation of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Glucagon and regulation of glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Gene ontology: tool for the unification of biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Abnormal alpha-cell function in diabetes. Response to carbohydrate and protein ingestion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130710

20 June 2018

Glycemic control in mice with targeted disruption of the glucagon receptor gene

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-12-281

21 January 2018

Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice

1 reference

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21 January 2018

Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-12-281

21 January 2018

iTRAQ experimental design for plasma biomarker discovery

1 reference

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21 January 2018

High-throughput and multiplexed LC/MS/MRM method for targeted metabolomics

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-12-281

21 January 2018

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

1 reference

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26 November 2018

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21631939

12 December 2020

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10.1186/1471-2164-12-281

1 reference

Europe PubMed Central

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2 February 2020

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/1471-2164-12-281

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Europe PubMed Central

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2 February 2020

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Europe PubMed Central

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2 February 2020

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