(Q30523756)

12 August 2017

Pseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeability (English)

1 reference

12 August 2017

Pseudomonas aeruginosa

0 references

0 references

1 reference

Cristhiaan D Ochoa

1

1 reference

12 August 2017

Mikhail Alexeyev

2

1 reference

12 August 2017

Viktoriya Pastukh

3

1 reference

12 August 2017

Ron Balczon

4

1 reference

12 August 2017

Troy Stevens

5

1 reference

12 August 2017

language of work or name

English

0 references

publication date

25 May 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

1 reference

12 August 2017

25407-25418

1 reference

12 August 2017

30

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3408204/fullTextXML

inferred from PubMed Central ID database lookup

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Adenosine monophosphate-activated kinase alpha1 promotes endothelial barrier repair

20 June 2018

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Tauopathies: one disease or many?

20 June 2018

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Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity

20 June 2018

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20 June 2018

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Cold exposure reveals two populations of microtubules in pulmonary endothelia

20 June 2018

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Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation

20 June 2018

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Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier

20 June 2018

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Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.

20 June 2018

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Myosin light chain kinase in microvascular endothelial barrier function

20 June 2018

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Perivascular fluid cuffs decrease lung compliance by increasing tissue resistance.

20 June 2018

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Caspase activation precedes and leads to tangles

20 June 2018

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20 June 2018

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A retro-lentiviral system for doxycycline-inducible gene expression and gene knockdown in cells with limited proliferative capacity

20 June 2018

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The tau of MARK: a polarized view of the cytoskeleton

20 June 2018

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Soluble adenylyl cyclase-dependent microtubule disassembly reveals a novel mechanism of endothelial cell retraction

20 June 2018

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Gene composer: database software for protein construct design, codon engineering, and gene synthesis

20 June 2018

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

20 June 2018

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The actin cytoskeleton in endothelial cell phenotypes

20 June 2018

1 reference

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Crystal structure of the guanylyl cyclase Cya2

20 June 2018

1 reference

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Lung vascular cell heterogeneity: endothelium, smooth muscle, and fibroblasts.

20 June 2018

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Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization

20 June 2018

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Pharmacological PKA inhibition: all may not be what it seems

20 June 2018

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Chlamydophila pneumoniae and the etiology of late-onset Alzheimer's disease

20 June 2018

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Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation

20 June 2018

1 reference

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Tauopathy models and human neuropathology: similarities and differences

20 June 2018

1 reference

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Tau aggregation and toxicity in a cell culture model of tauopathy

20 June 2018

1 reference

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A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

20 June 2018

1 reference

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Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau

20 June 2018

1 reference

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Signaling mechanisms regulating endothelial permeability

20 June 2018

1 reference

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Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

20 June 2018

1 reference

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The adenylate cyclase toxins

20 June 2018

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A therapeutic strategy against the shared virulence mechanism utilized by both Yersinia pestis and Pseudomonas aeruginosa

20 June 2018

1 reference

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Infiltration of the brain by pathogens causes Alzheimer's disease

20 June 2018

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Structure, function and evolution of microbial adenylyl and guanylyl cyclases

20 June 2018

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The multi-talented bacterial adenylate cyclases

20 June 2018

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Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms.

20 June 2018

1 reference

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The Dictyostelium homologue of mammalian soluble adenylyl cyclase encodes a guanylyl cyclase

20 June 2018

1 reference

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cAMP-dependent vasodilators cross-activate the cGMP-dependent protein kinase to stimulate BK(Ca) channel activity in coronary artery smooth muscle cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Differential assembly of human tau isoforms in the presence of arachidonic acid

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Microvascular permeability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Elevation of guanosine 3',5'-cyclic phosphate in rat heart after perfusion with acetylcholine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Beta-adrenergic agonists increase lung liquid clearance in anesthetized sheep

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Biologic regulation through opposing influences of cyclic GMP and cyclic AMP: the Yin Yang hypothesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Myoendothelial gap junctional signaling induces differentiation of pulmonary arterial smooth muscle cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

{alpha}MSH and Cyclic AMP elevating agents control melanosome pH through a protein kinase A-independent mechanism.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Levels of soluble and insoluble tau reflect overall status of tau phosphorylation in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Heterogeneity of barrier function in the lung reflects diversity in endothelial cell junctions

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Synthesis and analysis of stabilizing ligands for FKBP-derived destabilizing domains

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Role of protein kinase G in barrier-protective effects of cGMP in human pulmonary artery endothelial cells

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Novel role of microtubules in thrombin-induced endothelial barrier dysfunction

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Pathogens as a cause of Alzheimer's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Structural and functional characteristics of lung macro- and microvascular endothelial cell phenotypes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Deducing the origin of soluble adenylyl cyclase, a gene lost in multiple lineages

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

cGMP-induced presynaptic depression and postsynaptic facilitation at glutamatergic synapses in visual cortex.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Microvascular permeability and number of tight junctions are modulated by cAMP.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408204

Hydraulic conductance of pulmonary microvascular and macrovascular endothelial cell monolayers

26 November 2018

1 reference

12 December 2020

Activation of Mitogen-activated Protein Kinase Pathways by Cyclic GMP and Cyclic GMP-dependent Protein Kinase in Contractile Vascular Smooth Muscle Cells

1 reference

12 December 2020

Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa

1 reference

12 December 2020

Glycogen Synthase Kinase 3β Is Activated by cAMP and Plays an Active Role in the Regulation of Melanogenesis

1 reference

12 December 2020

Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.301440

1 reference

12 August 2017

1 reference

12 August 2017

1 reference