(Q30525001)

19 October 2017

INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells (English)

1 reference

19 October 2017

Laura Andrés-Delgado

1

1 reference

19 October 2017

Olga M Antón

2

1 reference

19 October 2017

Francesca Bartolini

3

1 reference

19 October 2017

Ana Ruiz-Sáenz

4

1 reference

19 October 2017

Isabel Correas

5

1 reference

19 October 2017

Gregg G Gundersen

6

1 reference

19 October 2017

Miguel A Alonso

7

1 reference

19 October 2017

language of work or name

English

0 references

publication date

1 September 2012

1 reference

19 October 2017

Journal of Cell Biology

1 reference

19 October 2017

198

1 reference

19 October 2017

6

1 reference

19 October 2017

1025-1037

1 reference

describes a project that uses

19 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3444772/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Casein kinase I delta controls centrosome positioning during T cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Centrosome docking at the immunological synapse is controlled by Lck signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Post-translational modifications of microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Plus-end-tracking proteins and their interactions at microtubule ends

20 June 2018

1 reference

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The immunological synapse: a focal point for endocytosis and exocytosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Functional anatomy of T cell activation and synapse formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Actin dynamics at the leading edge: from simple machinery to complex networks.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

20 June 2018

Formins and microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Motor-dependent microtubule disassembly driven by tubulin tyrosination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Nck adapter proteins: functional versatility in T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

20 June 2018

1 reference

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An experimental and computational study of effects of microtubule stabilization on T-cell polarity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Beyond polymer polarity: how the cytoskeleton builds a polarized cell

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

MTOC translocation modulates IS formation and controls sustained T cell signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Microtubule stabilization specifies initial neuronal polarization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Secretory mechanisms in cell-mediated cytotoxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Mechanism and function of formins in the control of actin assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Regulation of T-cell activation by the cytoskeleton

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Recruitment of dynein to the Jurkat immunological synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

A vital role of tubulin-tyrosine-ligase for neuronal organization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

A plus-end raft to control microtubule dynamics and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

mDia mediates Rho-regulated formation and orientation of stable microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Differential clustering of CD4 and CD3zeta during T cell recognition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

TCR, LFA-1, and CD28 play unique and complementary roles in signaling T cell cytoskeletal reorganization.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Effects of taxol and taxol/hyperthermia treatments on the functional polarization of cytotoxic T lymphocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Selective stabilization of microtubules oriented toward the direction of cell migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

Formin INF2 regulates MAL-mediated transport of Lck to the plasma membrane of human T lymphocytes

20 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Substoichiometric binding of taxol suppresses microtubule dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Centrosome polarization delivers secretory granules to the immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Tyrosine phosphorylation of α tubulin in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

26 November 2018

Identifiers

DOI

10.1083/JCB.201202137

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

22986496

1 reference