(Q30532862)

English

Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression (English)

1 reference

Europe PubMed Central

14 August 2017

Simian immunodeficiency virus

0 references

Netanya G. Sandler

object named as

Netanya G Sandler

10

0 references

object named as

Bapi Pahar

13

0 references

16

object named as

Brandon F Keele

1 reference

Europe PubMed Central

14 August 2017

11

object named as

Daniel C Douek

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Europe PubMed Central

14 August 2017

15

object named as

Jeffrey D Lifson

1 reference

Europe PubMed Central

14 August 2017

14

object named as

Michael Piatak

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Europe PubMed Central

14 August 2017

17

object named as

James A Hoxie

1 reference

Europe PubMed Central

14 August 2017

Beth S Haggarty

7

object named as

Beth S Haggarty

1 reference

Europe PubMed Central

14 August 2017

author name string

Matthew W Breed

1

1 reference

Europe PubMed Central

14 August 2017

Andrea P O Jordan

2

1 reference

Europe PubMed Central

14 August 2017

Pyone P Aye

3

1 reference

Europe PubMed Central

14 August 2017

Cornelis F Lichtveld

4

1 reference

Europe PubMed Central

14 August 2017

Cecily C Midkiff

5

1 reference

Europe PubMed Central

14 August 2017

Faith R Schiro

6

1 reference

Europe PubMed Central

14 August 2017

Chie Sugimoto

8

1 reference

Europe PubMed Central

14 August 2017

Xavier Alvarez

9

1 reference

Europe PubMed Central

14 August 2017

Marcelo J Kuroda

12

1 reference

Europe PubMed Central

14 August 2017

Andrew A Lackner

18

1 reference

Europe PubMed Central

14 August 2017

publication date

14 November 2012

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Europe PubMed Central

14 August 2017

Journal of Virology

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Europe PubMed Central

14 August 2017

87

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Europe PubMed Central

14 August 2017

3

1 reference

Europe PubMed Central

14 August 2017

1528-1543

1 reference

Europe PubMed Central

14 August 2017

Natural SIV hosts: showing AIDS the door

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Dynamics of innate immunity are key to chronic immune activation in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Systems biology of natural simian immunodeficiency virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques

1 reference

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14 July 2018

Generalized immune activation and innate immune responses in simian immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression

1 reference

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14 July 2018

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques

1 reference

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14 July 2018

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

1 reference

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14 July 2018

Plasma levels of soluble CD14 independently predict mortality in HIV infection

1 reference

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14 July 2018

Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV

1 reference

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14 July 2018

Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

1 reference

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14 July 2018

Neurokinin-1 receptor (NK1-R) expression in the brains of SIV-infected rhesus macaques: implications for substance P in NK1-R immune cell trafficking into the CNS

1 reference

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14 July 2018

Protection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV.

1 reference

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14 July 2018

Nonprogressive and progressive primate immunodeficiency lentivirus infections

1 reference

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14 July 2018

Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge

1 reference

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14 July 2018

Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA

1 reference

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14 July 2018

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS

1 reference

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14 July 2018

Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma

1 reference

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14 July 2018

Resolution of immune activation defines nonpathogenic SIV infection

1 reference

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14 July 2018

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Disruption of an env tyrosine-dependent sorting signal does not affect susceptibility of HIV-1 to cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Cell-to-cell HIV-1 spread and its implications for immune evasion

1 reference

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14 July 2018

Quantitative 3D video microscopy of HIV transfer across T cell virological synapses

1 reference

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14 July 2018

Glycerol monolaurate prevents mucosal SIV transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion

1 reference

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Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

1 reference

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14 July 2018

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

The structural biology of HIV assembly

1 reference

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14 July 2018

Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

CD163, a marker of perivascular macrophages, is up-regulated by microglia in simian immunodeficiency virus encephalitis after haptoglobin-hemoglobin complex stimulation and is suggestive of breakdown of the blood-brain barrier

1 reference

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14 July 2018

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

HIV disease progression: immune activation, microbes, and a leaky gut.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Massive infection and loss of CD4+ T cells occurs in the intestinal tract of neonatal rhesus macaques in acute SIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection

1 reference

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14 July 2018

Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

1 reference

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Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts

1 reference

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Role of viral splicing elements and cellular RNA binding proteins in regulation of HIV-1 alternative RNA splicing

1 reference

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HIV vaccine design: insights from live attenuated SIV vaccines

1 reference

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14 July 2018

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

1 reference

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14 July 2018

HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway

1 reference

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14 July 2018

Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesis

1 reference

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14 July 2018

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

1 reference

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14 July 2018

Monocyte/macrophage traffic in HIV and SIV encephalitis

1 reference

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14 July 2018

Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys

1 reference

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14 July 2018

Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251.

1 reference

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14 July 2018

SIV(mac) pathogenesis in rhesus macaques of Chinese and Indian origin compared with primary HIV infections in humans

1 reference

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14 July 2018

Mechanisms of protection against simian immunodeficiency virus infection

1 reference

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14 July 2018

Efficient class I major histocompatibility complex down-regulation by simian immunodeficiency virus Nef is associated with a strong selective advantage in infected rhesus macaques

1 reference

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14 July 2018

Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS.

1 reference

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14 July 2018

The simian immunodeficiency virus envelope glycoprotein contains multiple signals that regulate its cell surface expression and endocytosis

1 reference

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14 July 2018

In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail

1 reference

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14 July 2018

Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophages

1 reference

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14 July 2018

Polarized human immunodeficiency virus budding in lymphocytes involves a tyrosine-based signal and favors cell-to-cell viral transmission

1 reference

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14 July 2018

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

1 reference

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14 July 2018

Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins

1 reference

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14 July 2018

Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.

1 reference

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14 July 2018

A membrane-proximal tyrosine-based signal mediates internalization of the HIV-1 envelope glycoprotein via interaction with the AP-2 clathrin adaptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

CD4: a co-receptor in the immune response and HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Complex determinants of macrophage tropism in env of simian immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

14 July 2018

Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

26 November 2018

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

26 November 2018

Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

26 November 2018

The basolateral targeting signal in the cytoplasmic domain of glycoprotein G from vesicular stomatitis virus resembles a variety of intracellular targeting motifs related by primary sequence but having diverse targeting activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554169

26 November 2018

HIV, mucosal tissues, and T helper 17 cells: where we come from, where we are, and where we go from here

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01928-12

1 reference

Europe PubMed Central

14 August 2017

release_npd3kyrfyjflzk7g5jt73bkhx4

1 reference

https://api.fatcat.wiki/v0/release/npd3kyrfyjflzk7g5jt73bkhx4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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