(Q30538184)

15 August 2017

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth (English)

1 reference

amyotrophic lateral sclerosis

15 August 2017

0 references

1 reference

based on heuristic

inferred from title

author

Christine Van Broeckhoven

16

Christine Van Broeckhoven

0 references

Julie van der Zee

6

Julie van der Zee

0 references

Julia Banzhaf-Strathmann

4

Julia Banzhaf-Strathmann

0 references

Christian Haass

19

Christian Haass

0 references

Maike Kittelmann

Maike Kittelmann

10

0 references

Stefan F Lichtenthaler

18

Stefan F Lichtenthaler

1 reference

15 August 2017

17

Dieter Edbauer

1 reference

15 August 2017

12

Marc Cruts

1 reference

15 August 2017

1

Bettina Schmid

1 reference

15 August 2017

Alexander Hruscha

2

1 reference

15 August 2017

Sebastian Hogl

3

1 reference

15 August 2017

Katrin Strecker

5

1 reference

15 August 2017

Mathias Teucke

7

1 reference

15 August 2017

Stefan Eimer

8

1 reference

15 August 2017

Jan Hegermann

9

1 reference

15 August 2017

Elisabeth Kremmer

11

1 reference

15 August 2017

Barbara Solchenberger

13

1 reference

15 August 2017

Laura Hasenkamp

14

1 reference

15 August 2017

Frauke van Bebber

15

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 March 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

110

1 reference

15 August 2017

13

1 reference

15 August 2017

4986-4991

1 reference

Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

The genetics and neuropathology of frontotemporal lobar degeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Locus-specific mutation databases for neurodegenerative brain diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Mutations in the N-terminal actin-binding domain of filamin C cause a distal myopathy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 regulates its mRNA levels through a negative feedback loop

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43-based animal models of neurodegeneration: new insights into ALS pathology and pathophysiology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Genome editing with engineered zinc finger nucleases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Gray matter perfusion correlates with disease severity in ALS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 is a developmentally regulated protein essential for early embryonic development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Characterization of vascular mural cells during zebrafish development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

VEGF at the neurovascular interface: therapeutic implications for motor neuron disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Common mechanisms of nerve and blood vessel wiring

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

A mutation in the dimerization domain of filamin c causes a novel type of autosomal dominant myofibrillar myopathy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

The many faces of filamin: a versatile molecular scaffold for cell motility and signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Characterization of muscle filamin isoforms suggests a possible role of gamma-filamin/ABP-L in sarcomeric Z-disc formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Filamin 2 (FLN2): A muscle-specific sarcoglycan interacting protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Amyotrophic lateral sclerosis

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

A window to the heart: can zebrafish mutants help us understand heart disease in humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

Filamin C plays an essential role in the maintenance of the structural integrity of cardiac and skeletal muscles, revealed by the medaka mutant zacro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

Characterization and investigation of zebrafish models of filamin-related myofibrillar myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

Constant blood flow reduction in premotor frontal lobe regions in ALS with dementia - a SPECT study with 3D-SSP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218311110

TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Filamin isogene expression during mouse myogenesis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3612625

Cerebral blood flow and oxygen metabolism in progressive dementia associated with amyotrophic lateral sclerosis

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23457265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Angiogenic network formation in the developing vertebrate trunk

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23457265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1218311110

1 reference

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

23457265

1 reference