(Q30540902)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Silvia Ravera

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Michela Massollo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Adriana Amaro

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Mario Passalacqua

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Ulrich Pfeffer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Renzo Cordera

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Davide Maggi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

13

Gianmario Sambuceti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Barbara Salani

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Alberto Del Rio

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Anna Maria Orengo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Sara Maffioli

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

English

0 references

publication date

1 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

2070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

3 March 2020

copyright license

start time

25 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3691576/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Metformin--an adjunct antineoplastic therapy--divergently modulates tumor metabolism and proliferation, interfering with early response prediction by 18F-FDG PET imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Investigating metformin for cancer prevention and treatment: the end of the beginning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Freely accessible databases of commercial compounds for high- throughput virtual screenings

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

X-ray crystallography: Assessment and validation of protein-small molecule complexes for drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Subcellular localization of hexokinases I and II directs the metabolic fate of glucose

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Evaluation of the role of hexokinase type II in cellular proliferation and apoptosis using human hepatocellular carcinoma cell lines.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Understanding the Warburg effect: the metabolic requirements of cell proliferation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Mitochondrial membrane permeabilization in cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Role of AMP-activated protein kinase in mechanism of metformin action

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691576

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

20 June 2018

1 reference

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Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP02070

Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP02070

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP02070

Cell biology. Why starving cells eat themselves

21 January 2018

1 reference

12 December 2020

Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors

1 reference

12 December 2020

Glut-1 and hexokinase expression: relationship with 2-fluoro-2-deoxy-D-glucose uptake in A431 and T47D cells in culture

1 reference

12 December 2020

Challenges in the determination of the binding modes of non-standard ligands in X-ray crystal complexes

1 reference

12 December 2020

The blooming of the French lilac

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI14178

Identifiers

DOI

10.1038/SREP02070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json