(Q30577853)

12 September 2017

Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature (English)

1 reference

12 September 2017

Mia Phillipson

1

1 reference

12 September 2017

Bryan Heit

2

1 reference

12 September 2017

Sean A Parsons

3

1 reference

12 September 2017

Björn Petri

4

1 reference

12 September 2017

Sarah C Mullaly

5

1 reference

12 September 2017

Pina Colarusso

6

1 reference

12 September 2017

R Michael Gower

7

1 reference

12 September 2017

Gregory Neely

8

1 reference

12 September 2017

Scott I Simon

9

1 reference

12 September 2017

Paul Kubes

10

1 reference

12 September 2017

language of work or name

English

0 references

publication date

1 June 2009

1 reference

12 September 2017

Journal of Immunology

1 reference

12 September 2017

182

1 reference

12 September 2017

11

1 reference

12 September 2017

6870-6878

1 reference

describes a project that uses

12 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4017595/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The physiology of leukocyte recruitment: an in vivo perspective.

20 June 2018

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Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins

20 June 2018

1 reference

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Neutrophil haptotaxis induced by mouse MNCF: interactions with extracellular matrix glycoproteins probably contribute to overcoming the anti-inflammatory action of dexamethasone

20 June 2018

1 reference

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VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2

20 June 2018

1 reference

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The role of the integrin LFA-1 in T-lymphocyte migration

20 June 2018

1 reference

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Small GTPases and LFA-1 reciprocally modulate adhesion and signaling

20 June 2018

1 reference

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Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade

20 June 2018

1 reference

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The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands

20 June 2018

1 reference

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Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Active leukocyte crawling in microvessels assessed by digital time-lapse intravital microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

G protein-coupled receptors serve as mechanosensors for fluid shear stress in neutrophils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The non-receptor tyrosine kinase Syk regulates lamellipodium formation and site-directed migration of human leukocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Pseudopod projection and cell spreading of passive leukocytes in response to fluid shear stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Regulation of CD18 expression on neutrophils in response to fluid shear stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The association between alpha4-integrin, P-selectin, and E-selectin in an allergic model of inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2 integrin (CD11/CD18)-mediated neutrophil migration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Preferential binding of leukocytes to the endothelial junction region in venules in situ.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Control of neutrophil pseudopods by fluid shear: role of Rho family GTPases

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Real-time analysis of very late antigen-4 affinity modulation by shear

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Locomotion of monocytes on endothelium is a critical step during extravasation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Shear flow-induced motility of Dictyostelium discoideum cells on solid substrate

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Role of p38 mitogen-activated protein kinase in chemokine-induced emigration and chemotaxis in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017595

Analysis of integrin (CD11b/CD18) movement during neutrophil adhesion and migration on endothelial cells

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19454683

12 December 2020

inferred from PubMed ID database lookup

CD99 is a key mediator of the transendothelial migration of neutrophils

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19454683

12 December 2020

inferred from PubMed ID database lookup

Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19454683

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4049/JIMMUNOL.0803414

1 reference

12 September 2017

1 reference

12 September 2017

PubMed publication ID

19454683

1 reference