(Q30580233)

20 September 2017

TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres (English)

1 reference

20 September 2017

Maria A Blasco

4

0 references

author name string

Martina Stagno d'Alcontres

series ordinal

1

1 reference

20 September 2017

Jose Alejandro Palacios

series ordinal

2

1 reference

20 September 2017

Diego Mejias

series ordinal

3

1 reference

20 September 2017

10 March 2014

1 reference

20 September 2017

1 reference

20 September 2017

13

1 reference

20 September 2017

9

1 reference

20 September 2017

1463-1481

1 reference

describes a project that uses

20 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4050144/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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All tangled up: how cells direct, manage and exploit topoisomerase function

20 June 2018

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PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution

20 June 2018

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A mitotic role for Mad1 beyond the spindle checkpoint

20 June 2018

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Analysis of human and mouse reprogramming of somatic cells to induced pluripotent stem cells. What is in the plate?

20 June 2018

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TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

20 June 2018

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Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites

20 June 2018

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TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice

20 June 2018

1 reference

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Persistent telomere damage induces bypass of mitosis and tetraploidy

20 June 2018

1 reference

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ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase

20 June 2018

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TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression

20 June 2018

1 reference

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In vivo stoichiometry of shelterin components

20 June 2018

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A non-canonical function of topoisomerase II in disentangling dysfunctional telomeres

20 June 2018

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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

20 June 2018

1 reference

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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

20 June 2018

1 reference

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The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

How shelterin protects mammalian telomeres

20 June 2018

1 reference

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Whole chromosome instability and cancer: a complex relationship

20 June 2018

1 reference

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Distinct roles of TRF1 in the regulation of telomere structure and lengthening

20 June 2018

1 reference

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Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation

20 June 2018

1 reference

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Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation

20 June 2018

1 reference

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20 June 2018

Chromosome fragile sites

1 reference

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BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

20 June 2018

1 reference

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The spindle-assembly checkpoint in space and time

20 June 2018

1 reference

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The epigenetic regulation of mammalian telomeres

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

The anaphase promoting complex/cyclosome: a machine designed to destroy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

BubR1 is involved in regulation of DNA damage responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

On the road to cancer: aneuploidy and the mitotic checkpoint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Timing and checkpoints in the regulation of mitotic progression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Targeted deletion reveals an essential function for the telomere length regulator Trf1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

A system for stable expression of short interfering RNAs in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Telomere maintenance by recombination in human cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Association of human DNA topoisomerase IIalpha with mitotic chromosomes in mammalian cells is independent of its catalytic activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Essential role of mouse telomerase in highly proliferative organs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Control of telomere length by the human telomeric protein TRF1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

A human telomeric protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Telomeres: structure and synthesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

A mammalian factor that binds telomeric TTAGGG repeats in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells

20 June 2018

1 reference

Topoisomerase II poisoning by ICRF-193.

21 January 2018

1 reference

Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint.

21 January 2018

1 reference

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

21 January 2018

1 reference

Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1.

21 January 2018

1 reference

Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

21 January 2018

1 reference

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

21 January 2018

1 reference

XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer.

21 January 2018

1 reference

A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050144

Semi-conservative DNA replication through telomeres requires Taz1

26 November 2018

1 reference

The telomere repeat binding protein Trf1 interacts with the spindle checkpoint protein Mad1 and Nek2 mitotic kinase

21 January 2018

1 reference

12 December 2020

DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos

1 reference

12 December 2020

Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

1 reference

12 December 2020

In vitro catenation and decatenation of DNA and a novel eucaryotic ATP-dependent topoisomerase

1 reference

12 December 2020

ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings

1 reference

12 December 2020

Yeast DNA topoisomerase II. An ATP-dependent type II topoisomerase that catalyzes the catenation, decatenation, unknotting, and relaxation of double-stranded DNA rings

1 reference

12 December 2020

The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres

1 reference

12 December 2020

Identifiers

DOI

10.4161/CC.28419

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

24626180

1 reference