(Q30671121)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10206346%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Investigation of S-farnesyl transferase substrate specificity with combinatorial tetrapeptide libraries (English)

1 reference

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4 December 2019

1

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4 December 2019

author name string

W Marande

2

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4 December 2019

L Petit

3

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4 December 2019

A Loynel

4

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4 December 2019

C Desmet

5

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4 December 2019

E Canet

6

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4 December 2019

J L Fauchère

7

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4 December 2019

publication date

1 January 1999

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4 December 2019

number of pages

11

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inferred from page(s)

published in

Cellular Signalling

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4 December 2019

volume

11

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4 December 2019

issue

1

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4 December 2019

page(s)

59-69

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New clue to Ras lipid glue

4 December 2019

cites work

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All ras proteins are polyisoprenylated but only some are palmitoylated

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Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

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7 January 2021

Protein prenylation: molecular mechanisms and functional consequences

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7 January 2021

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

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7 January 2021

Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases

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7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

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7 January 2021

The potential of farnesyltransferase inhibitors as cancer chemotherapeutics

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7 January 2021

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

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7 January 2021

Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I

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7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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7 January 2021

Myristoyl-CoA:protein N-myristoyltransferase activity in cancer cells. Purification and characterization of a cytosolic isoform from the murine leukemia cell line L1210.

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7 January 2021

Substrate phosphorylation capacities of the major tyrosine protein kinase from the human promyelocytic cell line, HL-60.

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7 January 2021

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

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7 January 2021

Combinatorial peptide libraries: robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry, and high-performance capillary electrophoresis techniques.

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7 January 2021

Chromatographic assay and peptide substrate characterization of partially purified farnesyl- and geranylgeranyltransferases from rat brain cytosol.

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7 January 2021

Limitations of the coupling of amino acid mixtures for the preparation of equimolar peptide libraries.

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7 January 2021

Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes

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7 January 2021

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7 January 2021

Fatty acylated proteins as components of intracellular signaling pathways

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7 January 2021

Inhibitors of the Ras signal transduction pathway as potential antitumour agents

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7 January 2021

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase

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7 January 2021

Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase

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7 January 2021

Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library

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7 January 2021

Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

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7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

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7 January 2021

Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors

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7 January 2021

The ras protein family: evolutionary tree and role of conserved amino acids

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7 January 2021

Protein prenylation: more than just glue?

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7 January 2021

Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries

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7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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7 January 2021

Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB

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7 January 2021

Enzymatic modification of proteins with a geranylgeranyl isoprenoid

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7 January 2021

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

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7 January 2021

The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands

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7 January 2021

CAAX geranylgeranyl transferase transfers farnesyl as efficiently as geranylgeranyl to RhoB

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7 January 2021

Differential prenyl pyrophosphate binding to mammalian protein geranylgeranyltransferase-I and protein farnesyltransferase and its consequence on the specificity of protein prenylation

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7 January 2021

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7 January 2021

Synergy between anions and farnesyldiphosphate competitive inhibitors of farnesyl:protein transferase

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7 January 2021

Amino acid side chain parameters for correlation studies in biology and pharmacology

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7 January 2021

Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation

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7 January 2021

Yersinia pestis pH 6 antigen forms fimbriae and is induced by intracellular association with macrophages

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7 January 2021

Pex19p, a farnesylated protein essential for peroxisome biogenesis

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10206346%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference