(Q30697899)

26 June 2017

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title

Thermodynamics of drug-DNA interactions (English)

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26 June 2017

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Ihtshamul Haq

1

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PubMed ID

12061796

26 June 2017

language of work or name

English

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publication date

1 July 2002

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Archives of Biochemistry and Biophysics

26 June 2017

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26 June 2017

403

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26 June 2017

1

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26 June 2017

1-15

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DNA as a target for drug action

26 June 2017

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Initial sequencing and analysis of the human genome

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Drug-DNA recognition: energetics and implications for design

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Thermodynamics of nucleic acids and their interactions with ligands

7 January 2021

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7 January 2021

Drug--DNA interactions.

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Energetics of drug-DNA interactions

7 January 2021

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Calorimetric techniques in the study of high-order DNA-drug interactions

7 January 2021

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Parsing free energies of drug-DNA interactions.

7 January 2021

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Criteria for the mode of binding of DNA binding agents.

7 January 2021

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Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

7 January 2021

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Analysis and interpretation of ligand-DNA binding isotherms

7 January 2021

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Surface plasmon resonance biosensor analysis of RNA-small molecule interactions

7 January 2021

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Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition

7 January 2021

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Sensing the heat: the application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions

7 January 2021

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Rapid measurement of binding constants and heats of binding using a new titration calorimeter

7 January 2021

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Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

7 January 2021

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The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

7 January 2021

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Limiting Laws and Counterion Condensation in Polyelectrolyte Solutions I. Colligative Properties

7 January 2021

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Ion effects on ligand-nucleic acid interactions

7 January 2021

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Calculation of the free energy of association for protein complexes

7 January 2021

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Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics

7 January 2021

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Coupling of local folding to site-specific binding of proteins to DNA

7 January 2021

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16 Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA

7 January 2021

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Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies

7 January 2021

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Energetics of DNA intercalation reactions

7 January 2021

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A thermodynamic and structural analysis of DNA minor-groove complex formation

7 January 2021

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7 January 2021

Angströms and calories

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Use of liquid hydrocarbon and amide transfer data to estimate contributions to thermodynamic functions of protein folding from the removal of nonpolar and polar surface from water

7 January 2021

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Contribution to the thermodynamics of protein folding from the reduction in water-accessible nonpolar surface area.

7 January 2021

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Extracting hydrophobic free energies from experimental data: relationship to protein folding and theoretical models

7 January 2021

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Reconciling the magnitude of the microscopic and macroscopic hydrophobic effects

7 January 2021

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Hydrophobic effect in protein folding and other noncovalent processes involving proteins

7 January 2021

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Role of the hydrophobic effect in stability of site-specific protein-DNA complexes

7 January 2021

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Binding of Hoechst 33258 and 4',6-diamidino-2-phenylindole to self-complementary decadeoxynucleotides with modified exocyclic base substituents

7 January 2021

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Significant discrepancies between van't Hoff and calorimetric enthalpies. II.

7 January 2021

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Significant discrepancies between van't Hoff and calorimetric enthalpies

7 January 2021

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Possible origin of differences between van't Hoff and calorimetric enthalpy estimates

7 January 2021

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2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents

7 January 2021

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Temperature dependence of enthalpy changes for ethidium and propidium binding to DNA: effect of alkylamine chains

7 January 2021

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Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design

7 January 2021

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The effect of water activity on the association constant and the enthalpy of reaction between lysozyme and the specific antibodies D1.3 and D44.1.

7 January 2021

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The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

7 January 2021

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The role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin A

7 January 2021

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Substrate specificity and affinity of a protein modulated by bound water molecules

7 January 2021

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Probing the hydration of the minor groove of A.T synthetic DNA polymers by volume and heat changes

7 January 2021

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Differential hydration of homopurine sequences relative to alternating purine/pyrimidine sequences

7 January 2021

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Hydration of dA.dT polymers: role of water in the thermodynamics of ethidium and propidium intercalation

7 January 2021

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Macromolecules and water: probing with osmotic stress

7 January 2021

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Effects of hydration, ion release, and excluded volume on the melting of triplex and duplex DNA

7 January 2021

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Participation of water in Hin recombinase--DNA recognition

7 January 2021

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Site-specific cation binding mediates TATA binding protein-DNA interaction from a hyperthermophilic archaeon

7 January 2021

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The osmotic sensitivity of netropsin analogue binding to DNA

7 January 2021

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Hydration changes for DNA intercalation reactions

7 January 2021

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Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin

7 January 2021

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The Entropic Cost of Bound Water in Crystals and Biomolecules

7 January 2021

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The question of long-range allosteric transitions in DNA

7 January 2021

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Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

7 January 2021

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Transmission of allosteric effects in DNA

7 January 2021

1 reference

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Interaction of netropsin and distamycin with deoxyribonucleic acid: electric dichroism study

7 January 2021

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Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2)

7 January 2021

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Cooperativity in drug-DNA recognition: a molecular dynamics study

7 January 2021

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Allostery without conformational change. A plausible model

7 January 2021

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The DNA sequence at echinomycin binding sites determines the structural changes induced by drug binding: NMR studies of echinomycin binding to [d(ACGTACGT)]2 and [d(TCGATCGA)]2.

7 January 2021

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Cooperativity in the binding of echinomycin to DNA fragments containing closely spaced CpG sites

7 January 2021

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10.1016/S0003-9861(02)00202-3

7 January 2021

Identifiers

DOI

1 reference

26 June 2017

1 reference

PubMed ID

12061796