(Q30928368)

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Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature

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scholarly article

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Europe PubMed Central

27 June 2017

Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature (English)

1 reference

Europe PubMed Central

27 June 2017

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Alzheimer's disease

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phosphorylation

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Johannes Kornhuber

7

object named as

Johannes Kornhuber

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Europe PubMed Central

27 June 2017

object named as

Jens Wiltfang

8

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Juan Manuel Maler

5

object named as

Juan Manuel Maler

1 reference

Europe PubMed Central

27 June 2017

1

object named as

Piotr Lewczuk

1 reference

Europe PubMed Central

27 June 2017

Hermann Esselmann

2

object named as

Hermann Esselmann

1 reference

Europe PubMed Central

27 June 2017

3

object named as

Mirko Bibl

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Europe PubMed Central

27 June 2017

author name string

Georg Beck

4

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Europe PubMed Central

27 June 2017

Markus Otto

6

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Europe PubMed Central

27 June 2017

language of work or name

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based on heuristic

inferred from title

publication date

1 January 2004

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Europe PubMed Central

27 June 2017

Journal of Molecular Neuroscience

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Europe PubMed Central

27 June 2017

23

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Europe PubMed Central

27 June 2017

115-122

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Europe PubMed Central

27 June 2017

1-2

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Europe PubMed Central

27 June 2017

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processes induced by tau expression in Sf9 cells have an axon-like microtubule organization

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CSF phosphorylated tau is a possible marker for discriminating Alzheimer's disease from dementia with Lewy bodies. Phospho-Tau International Study Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice.

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consensus report of the Working Group on: "Molecular and Biochemical Markers of Alzheimer's Disease". The Ronald and Nancy Reagan Research Institute of the Alzheimer's Association and the National Institute on Aging Working Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered microtubule organization in small-calibre axons of mice lacking tau protein

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal beta-amyloid ((1-42)) in early Alzheimer's disease: association with apolipoprotein E genotype and cognitive decline.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid tau and beta-amyloid(1-42) in dementia disorders

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of tau in a nonneuronal cell induces long cellular processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological stageing of Alzheimer-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

“Mini-mental state”

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid phospho-tau, total tau and beta-amyloid(1-42) in the differentiation between Alzheimer's disease and vascular dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Auguste D and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CSF phosphorylated tau protein and mild cognitive impairment: a prospective study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of tau phosphorylated at threonine 231 in cerebrospinal fluid of Alzheimer's disease patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CSF total tau, Abeta42 and phosphorylated tau protein as biomarkers for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions and malfunctions of the tau proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt–Jakob disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental expression of tau proteins in the chicken and rat brain: rapid down-regulation of a paired helical filament epitope in the rat cerebral cortex coincides with the transition from immature to adult tau isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15126697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/JMN:23:1-2:115

1 reference

Europe PubMed Central

27 June 2017

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0 references

1 reference

Europe PubMed Central

27 June 2017

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