(Q31010361)

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A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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28 February 2020

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Gordon B. Mills

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Gordon B Mills

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28 February 2020

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Azadeh Cheraghchi-Bashi

1

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28 February 2020

Christine A Parker

2

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28 February 2020

Jean-Frederic Salazar

4

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28 February 2020

Hatice Gungor

5

1 reference

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28 February 2020

Azeem Saleem

6

1 reference

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28 February 2020

Paula Cunnea

7

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28 February 2020

Nona Rama

8

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28 February 2020

Cristian Salinas

9

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28 February 2020

Shannon R Morris

11

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28 February 2020

Rakesh Kumar

12

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28 February 2020

Euan A Stronach

14

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28 February 2020

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1 December 2015

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28 February 2020

1 reference

Europe PubMed Central

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28 February 2020

6

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28 February 2020

39

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28 February 2020

41736-41749

1 reference

Europe PubMed Central

PMC publication ID

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28 February 2020

Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Dissecting "PI3Kness": the complexity of personalized therapy for ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

An ATP-site on-off switch that restricts phosphatase accessibility of Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Rethinking ovarian cancer: recommendations for improving outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Functional proteomic analysis of advanced serous ovarian cancer using reverse phase protein array: TGF-beta pathway signaling indicates response to primary chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Gene set enrichment analysis made simple

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Inhibitor hijacking of Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a Phase III Trial of the Gynecologic Cancer Intergroup

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Pharmacodynamic biomarkers for molecular cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

14 July 2018

Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

25 November 2018

MAPK and PI3K/AKT mediated YB-1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

25 November 2018

The genesis and evolution of high-grade serous ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

25 November 2018

Phosphorylation by Akt disables the anti-oncogenic activity of YB-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

25 November 2018

RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4747185

25 November 2018

Use of pharmacokinetic/pharmacodynamic biomarkers to support rational cancer drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/26497682

12 December 2020

based on heuristic

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10.18632/ONCOTARGET.6153

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497682%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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