(Q31026926)

14 October 2017

Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain (English)

1 reference

14 October 2017

Molecular Recognition of Protein Surfaces: High Affinity Ligands for the CBP KIX Domain (English)

1 reference

interface and colloid science

3 April 2024

main subject

1 reference

3 April 2024

1 reference

3 April 2024

3

Alanna Schepartz

1 reference

14 October 2017

Stacey E. Rutledge

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

3 April 2024

Heather M. Volkman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

3 April 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

14 October 2017

26 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14624582

full work available at URL

3 April 2024

https://europepmc.org/articles/pmc2926944?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

https://europepmc.org/articles/PMC2926944

3 April 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

https://europepmc.org/articles/PMC2926944?pdf=render

3 April 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

https://doi.org/10.1021/ja034508o

3 April 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14624582

https://pubs.acs.org/doi/pdf/10.1021/ja034508o

3 April 2024

1 reference

Journal of the American Chemical Society

3 April 2024

published in

1 reference

14 October 2017

125

1 reference

14 October 2017

47

1 reference

14 October 2017

14336-14347

1 reference

The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

A view to a kill: ligands for Bcl-2 family proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Polyproline II structure in a sequence of seven alanine residues.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Polyproline II helical structure in protein unfolded states: lysine peptides revisited

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

The emerging power of chemical genetics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Protein-protein interfaces: mimics and inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Design and Evolution of a Miniature Bcl-2 Binding Protein We thank the HHMI Biopolymer/Keck Foundation Biotechnology Resource Laboratory (Yale University School of Medicine, New Haven, CT) for oligonucleotide and peptide synthesis and amino acid ana

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Concerted evolution of structure and function in a miniature protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Life-or-death decisions by the Bcl-2 protein family.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Small-molecule inhibitors of cell signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Minimal activators that bind to the KIX domain of p300/CBP identified by phage display screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Structural chemistry and therapeutic intervention of protein-protein interactions in immune response, human immunodeficiency virus entry, and apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Antagonists of protein-protein interactions.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

21 June 2018

The Bcl-2 protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Role of secondary structure in discrimination between constitutive and inducible activators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

A survey of left-handed polyproline II helices

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

The atomic structure of protein-protein recognition sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Conformational preferences in the Ser133-phosphorylated and non-phosphorylated forms of the kinase inducible transactivation domain of CREB

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Principles of protein-protein interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Conformational flexibility in a small globular hormone: x-ray analysis of avian pancreatic polypeptide at 0.98-A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

An exact correction to the "Cheng-Prusoff" correction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Chemical genetics resulting from a passion for synthetic organic chemistry.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Molecular interactions between the coactivator CBP and the human T-cell leukemia virus Tax protein

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926944

Synthesis of tetrocarcin derivatives with specific inhibitory activity towards Bcl-2 functions

25 November 2018

1 reference

12 December 2020

Electrostatic contribution of phosphorylation to the stability of the CREB-CBP activator-coactivator complex

1 reference

12 December 2020

Miniature Homeodomains: High Specificity without an N-Terminal Arm

1 reference

12 December 2020

Interaction, assembly and processing At the chemistry-biology interface

1 reference

12 December 2020

Transcriptional activator-coactivator recognition: nascent folding of a kinase-inducible transactivation domain predicts its structure on coactivator binding

1 reference

12 December 2020

From Knowing to Controlling: A Path from Genomics to Drugs Using Small Molecule Probes

5

1 reference

Chemical genetics: tailoring tools for cell biology

3 April 2024

6

1 reference

A diverse set of oligomeric class II MHC-peptide complexes for probing T-cell receptor interactions

3 April 2024

8

1 reference

Target-oriented and diversity-oriented organic synthesis in drug discovery

3 April 2024

10

1 reference

Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

3 April 2024

11

1 reference

Journal of Molecular Biology

3 April 2024

14

285

2198

Lo Conte L.

1999

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 April 2024

15

93

20

Jones S.

1996

1 reference

Bioorganic & Medicinal Chemistry Letters

3 April 2024

17

11

1505

Chin J. W.

2001

1 reference

Journal of the American Chemical Society

3 April 2024

18

123

2930

Chin J. W.

2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 April 2024

27

97

7129

Wang J. L.

2000

1 reference

Journal of Medicinal Chemistry

3 April 2024

31

44

4324

Enyedy I. J.

2001

1 reference

Journal of Biological Chemistry

3 April 2024

36

277

248

Zor T.

2002

1 reference

Journal of Biological Chemistry

3 April 2024

47

277

174

Goto N. K.

2002

1 reference

Journal of Molecular Biology

3 April 2024

49

281

400

Yan J. P.

1998

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 April 2024

51

99

9195

Shi Z.

2002

1 reference

3 April 2024

Identifiers

DOI

10.1021/JA034508O

1 reference

14 October 2017

1 reference

14 October 2017

1 reference