(Q31034193)

English

Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach (English)

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

author name string

D Chen

1

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

C Hackbarth

2

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Z J Ni

3

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

C Wu

4

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

W Wang

5

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

R Jain

6

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Y He

7

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

K Bracken

8

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

B Weidmann

9

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

D V Patel

10

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

J Trias

11

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

R J White

12

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Z Yuan

13

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

language of work or name

0 references

publication date

1 January 2004

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

48

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

250-261

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Protease inhibitors: current status and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Iron center, substrate recognition and mechanism of peptide deformylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Control of peptide deformylase activity by metal cations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Purification, characterization, and inhibition of peptide deformylase from Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

A survey of polypeptide deformylase function throughout the eubacterial lineage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Evidence that peptide deformylase and methionyl-tRNA(fMet) formyltransferase are encoded within the same operon in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

N-formylmethionyl-sRNA as the initiator of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

On the release of the formyl group from nascent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

21 June 2018

α-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Binding affinities and geometries of various metal ligands in peptide deformylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Deformylase as a novel antibacterial target.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Synthesis and antibacterial activity of peptide deformylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Mapping of the active site zinc ligands of peptide deformylase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=310177

25 November 2018

Formate dehydrogenase-coupled spectrophotometric assay of peptide deformylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14693547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation of protein synthesis in isolated mitochondria and chloroplasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14693547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen-mediated inactivation of peptide deformylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14693547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies concerning the antibiotic actinonin. Part VIII. Structure-activity relationships in the actinonin series

1 reference

https://pubmed.ncbi.nlm.nih.gov/14693547

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.48.1.250-261.2004

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

ResearchGate publication ID

0 references

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