(Q27639382)

English

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents

scientific article

In more languages

Statements

scholarly article

0 references

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents (English)

0 references

crystal structure

0 references

0 references

2

0 references

Thierry Meinnel

9

object named as

Thierry Meinnel

0 references

Carmela Giglione

object named as

Carmela Giglione

3

0 references

author name string

Jean-Pierre Guilloteau

1

0 references

Véronique Blanc

4

0 references

Alain Dupuy

5

0 references

Miline Chevrier

6

0 references

Patricia Gil

7

0 references

Alain Famechon

8

0 references

Vincent Mikol

10

0 references

language of work or name

0 references

publication date

26 July 2002

0 references

Journal of Molecular Biology

0 references

320

0 references

5

0 references

951-62

0 references

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

On the release of the formyl group from nascent protein

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Deformylation and protein biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Protein chain initiation and deformylation in B. subtilis homogenates

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Interplay of Methionine tRNAs with Translation Elongation Factor Tu and Translation Initiation Factor 2 inEscherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase as an antibacterial drug target: target validation and resistance development

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Distinctive features of the two classes of eukaryotic peptide deformylases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase: a target for novel antibiotics?

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Deformylase as a novel antibacterial target.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Enzymatic properties of Escherichia coli peptide deformylase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Control of peptide deformylase activity by metal cations.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Characterization of cobalt(II)-substituted peptide deformylase: function of the metal ion and the catalytic residue Glu-133.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Actinonin: an Antibiotic Substance produced by an Actinomycete

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Studies concerning the antibiotic actinonin. Part I. The constitution of actinonin. A natural hydroxamic acid with antibiotic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Mapping of the active site zinc ligands of peptide deformylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Substrate recognition and selectivity of peptide deformylase. Similarities and differences with metzincins and thermolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Solution structure of nickel-peptide deformylase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

The C-terminal domain of peptide deformylase is disordered and dispensable for activity

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Iron center, substrate recognition and mechanism of peptide deformylase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Crystal structure of the Escherichia coli peptide deformylase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

YkrB is the main peptide deformylase in Bacillus subtilis, a eubacterium containing two functional peptide deformylases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Design and Synthesis of Substrate Analogue Inhibitors of Peptide Deformylase†

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Resistance to anti-peptide deformylase drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

In vitro activities of peptide deformylase inhibitors against gram-positive pathogens

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Peptide deformylase as an emerging target for antiparasitic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Multiple sequence alignment with Clustal X

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

PROMOTIF--a program to identify and analyze structural motifs in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900549-1

7 January 2021

Identifiers

10.1016/S0022-2836(02)00549-1

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27639382&oldid=1373887481"