(Q31049476)

28 June 2017

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title

Integrating in vitro ADMET data through generic physiologically based pharmacokinetic models (English)

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28 June 2017

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David E Leahy

1

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28 June 2017

language of work or name

English

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publication date

1 August 2006

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Expert Opinion on Drug Metabolism & Toxicology

28 June 2017

published in

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28 June 2017

volume

2

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28 June 2017

issue

4

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28 June 2017

page(s)

619-628

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Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective

28 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

High-throughput approaches for evaluating absorption, distribution, metabolism and excretion properties of lead compounds

21 January 2018

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An analysis of the proposed REACH regulation

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Progress in simulation modelling for pharmacokinetics

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Physiologically-based pharmacokinetic simulation modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in rat plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Physiologic modeling of cyclosporin kinetics in rat and man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. I. Clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Allometric scaling of pharmacokinetic parameters in drug discovery: can human CL, Vss and t1/2 be predicted from in-vivo rat data?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Within- and between- subject variability in methadone pharmacokinetics and pharmacodynamics in methadone maintenance subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Pharmacokinetic variability of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

Physiologically Based Pharmacokinetic Modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2.4.619

21 January 2018

Identifiers

DOI

10.1517/17425255.2.4.619

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28 June 2017

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