(Q31099140)

English

High-affinity CRF1 receptor antagonist NBI-34041: preclinical and clinical data suggest safety and efficacy in attenuating elevated stress response

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 June 2017

High-affinity CRF1 receptor antagonist NBI-34041: preclinical and clinical data suggest safety and efficacy in attenuating elevated stress response (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Florian Holsboer

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object named as

Florian Holsboer

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4

object named as

Manfred Uhr

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1

object named as

Marcus Ising

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author name string

Ulrich S Zimmermann

2

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Heike E Künzel

3

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Europe PubMed Central

PubMed publication ID

28 June 2017

Alan C Foster

5

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Susan M Learned-Coughlin

6

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Europe PubMed Central

PubMed publication ID

28 June 2017

Dimitri E Grigoriadis

8

1 reference

Europe PubMed Central

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28 June 2017

language of work or name

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publication date

7 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Neuropsychopharmacology

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Europe PubMed Central

PubMed publication ID

28 June 2017

32

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Europe PubMed Central

PubMed publication ID

28 June 2017

9

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Europe PubMed Central

PubMed publication ID

28 June 2017

1941-1949

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Europe PubMed Central

PubMed publication ID

28 June 2017

Psychiatric implications of basic and clinical studies with corticotropin-releasing factor

1 reference

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21 January 2018

Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

21 January 2018

CSF corticotropin-releasing hormone in depressed patients and normal control subjects

1 reference

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21 January 2018

Corticotropin-releasing factor receptor antagonists in affective disorders and drug dependence-- an update

1 reference

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21 January 2018

Corticotropin releasing hormone receptors: two decades later

1 reference

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7 January 2021

based on heuristic

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CRF signaling: molecular specificity for drug targeting in the CNS.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating and 'anxiogenic' effects of corticotropin releasing factor are not inhibited by blockade of the pituitary-adrenal system with dexamethasone

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Stress and the brain: from adaptation to disease

1 reference

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7 January 2021

based on heuristic

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Dimensions of arousal: wakefulness and vigor.

1 reference

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7 January 2021

based on heuristic

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The corticotropin-releasing factor receptor: a novel target for the treatment of depression and anxiety-related disorders

1 reference

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7 January 2021

based on heuristic

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Design and synthesis of tricyclic corticotropin-releasing factor-1 antagonists

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: Relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression☆

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

The combined dexamethasone/CRH test as a potential surrogate marker in depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment with a CRH-1-receptor antagonist (R121919) does not affect weight or plasma leptin concentration in patients with major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuropeptide concentrations in the cerebrospinal fluid of depressed patients treated with electroconvulsive therapy. Corticotrophin-releasing factor, beta-endorphin and somatostatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Foot-shock induced stress increases β-endorphin levels in blood but not brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Antagonists of the corticotropin releasing factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

The neurobiology of urocortin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Age- and stimulus-dependent changes in anxiety-related behaviour of transgenic mice with GR dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of ethanol on hypothalamic-pituitary-adrenal system response to psychosocial stress in sons of alcohol-dependent fathers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

The therapeutic potential of CRF1 antagonists for anxiety

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301328

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.NPP.1301328

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

ResearchGate publication ID

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