(Q31108876)

28 June 2017

1 reference

title

Target validation and drug discovery using genomic and protein-protein interaction technologies (English)

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protein-protein interaction

28 June 2017

1 reference

1 reference

Renuka C Pillutla

1

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28 June 2017

Paul B Fisher

series ordinal

2

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28 June 2017

Arthur J Blume

series ordinal

3

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28 June 2017

Neil I Goldstein

series ordinal

4

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28 June 2017

language of work or name

English

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publication date

1 August 2002

1 reference

Expert Opinion on Therapeutic Targets

28 June 2017

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28 June 2017

6

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28 June 2017

4

1 reference

28 June 2017

517-531

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Drug discovery: a historical perspective

28 June 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A hierarchical approach to protein molecular evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Novel folded protein domains generated by combinatorial shuffling of polypeptide segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Recent developments in computational proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The promise of structural genomics in the discovery of new antimicrobial agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Domain combinations in archaeal, eubacterial and eukaryotic proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Domain repertoires as a tool to derive protein recognition rules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Identification and temporal expression pattern of genes modulated during irreversible growth arrest and terminal differentiation in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Microarrays: biotechnology's discovery platform for functional genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Reciprocal subtraction differential RNA display: an efficient and rapid procedure for isolating differentially expressed gene sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Serial analysis of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Subtractive cloning: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Subtractive hybridization--genetic takeaways and the search for meaning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Comparative genomic analysis of tumors: detection of DNA losses and amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Identifying differences in mRNA expression by representational difference analysis of cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Cooperation between AP1 and PEA3 sites within the progression elevated gene-3 (PEG-3) promoter regulate basal and differential expression of PEG-3 during progression of the oncogenic phenotype in transformed rat embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

PEA3 sites within the progression elevated gene-3 (PEG-3) promoter and mitogen-activated protein kinase contribute to differential PEG-3 expression in Ha-ras and v-raf oncogene transformed rat embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Development of a facile method for high throughput screening with reporter gene assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Different strategies of differential display: areas of application

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Differential display of mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Cloning differentially expressed mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Functional organization of the yeast proteome by systematic analysis of protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A generic protein purification method for protein complex characterization and proteome exploration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Global analysis of protein activities using proteome chips

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

High-throughput yeast two-hybrid assays for large-scale protein interaction mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Transcriptional transactivation by selected short random peptides attached to lexA-GFP fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A three-hybrid system to detect RNA-protein interactions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Using the yeast three-hybrid system to detect and analyze RNA-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Toward a protein-protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A comprehensive two-hybrid analysis to explore the yeast protein interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Protein interaction verification and functional annotation by integrated analysis of genome-scale data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Comparative assessment of large-scale data sets of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Dominant effector genetics in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Transdominant genetic analysis of a growth control pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A novel in vivo assay for the analysis of protein-protein interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Applications of display technology in protein analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Structural and mechanistic determinants of affinity and specificity of ligands discovered or engineered by phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Display of biologically active proteins on the surface of filamentous phages: a cDNA cloning system for selection of functional gene products linked to the genetic information responsible for their production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

T7 phage display: a novel genetic selection system for cloning RNA-binding proteins from cDNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Mapping signal transduction pathways by phage display.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

RNA-peptide fusions for the in vitro selection of peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

A surrogate-based approach for post-genomic partner identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Teamed up for transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

Negative effect of the transcriptional activator GAL4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.6.4.517

21 January 2018

Identifiers

DOI

10.1517/14728222.6.4.517

1 reference

28 June 2017

1 reference