(Q31120020)

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Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism

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Europe PubMed Central

PMC publication ID

17 August 2017

Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism (English)

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Europe PubMed Central

PMC publication ID

17 August 2017

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Ron S Ronimus

6

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Sean L McGee

7

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Cristin G Print

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Susan Richter

1

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Europe PubMed Central

PMC publication ID

17 August 2017

Shona Morrison

2

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Europe PubMed Central

PMC publication ID

17 August 2017

Tim Connor

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jiechuang Su

4

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Europe PubMed Central

PMC publication ID

17 August 2017

William R Wilson

8

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Europe PubMed Central

PMC publication ID

17 August 2017

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publication date

14 June 2013

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Europe PubMed Central

PMC publication ID

17 August 2017

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

e65267

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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Creative Commons Attribution 4.0 International

14 June 2013

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April 2022 Public Data File from Crossref

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3683018/fullTextXML

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limma

2 references

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3683018

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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affy

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

GeneSetDB: A comprehensive meta-database, statistical and visualisation framework for gene set analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Zinc finger nucleases: looking toward translation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Zinc-finger nucleases: how to play two good hands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

1 reference

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21 June 2018

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

An unbiased genome-wide analysis of zinc-finger nuclease specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

1 reference

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21 June 2018

Otto Warburg's contributions to current concepts of cancer metabolism

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21 June 2018

Hallmarks of Cancer: The Next Generation

1 reference

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21 June 2018

Regulation of cancer cell metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Zinc-finger nucleases: a panoramic view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Genome editing with engineered zinc finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Enhancement of DNA uptake in FUT8-deleted CHO cells for transient production of afucosylated antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

1 reference

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21 June 2018

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Hypoxia signalling through mTOR and the unfolded protein response in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Cytogenetic harvesting of commonly used tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

A novel function for cadherin 11/osteoblast-cadherin in vascular smooth muscle cells: modulation of cell migration and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology

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21 June 2018

Efficient gene targeting in Drosophila with zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

1 reference

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21 June 2018

Mutation detection using Surveyor nuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Cloning and biochemical characterization of a novel mouse ADP-dependent glucokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Summaries of Affymetrix GeneChip probe level data

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21 June 2018

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

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21 June 2018

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

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21 June 2018

Evidence for the operation of a novel Embden-Meyerhof pathway that involves ADP-dependent kinases during sugar fermentation by Pyrococcus furiosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683018

21 June 2018

Expression and role in glycolysis of human ADP-dependent glucokinase.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065267

21 January 2018

BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065267

21 January 2018

Hexokinase II acts through UCP3 to suppress mitochondrial reactive oxygen species production and maintain aerobic respiration.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065267

21 January 2018

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment

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25 November 2018

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12 December 2020

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10.1371/JOURNAL.PONE.0065267

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Europe PubMed Central

PMC publication ID

17 August 2017

2013PLoSO...865267R

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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