(Q40003411)

16 September 2017

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells (English)

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16 September 2017

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4

J Keith Joung

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16 September 2017

Shondra M Pruett-Miller

1

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16 September 2017

Jon P Connelly

2

1 reference

16 September 2017

Morgan L Maeder

3

1 reference

16 September 2017

Matthew H Porteus

5

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16 September 2017

4 March 2008

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16 September 2017

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16 September 2017

16

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16 September 2017

4

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16 September 2017

707-717

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Homologous recombination-mediated double-strand break repair

16 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Yeast transformation: a model system for the study of recombination

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Chimeric nucleases stimulate gene targeting in human cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Reverse genetic studies of the DNA damage response in the chicken B lymphocyte line DT40.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Design and packaging of adeno-associated virus gene targeting vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Homing endonucleases: keeping the house in order

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Homing endonuclease structure and function

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Gene targeting using zinc finger nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Chimeric restriction enzymes: what is next?

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Chimeric restriction endonuclease

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Binding studies with mutants of Zif268. Contribution of individual side chains to binding affinity and specificity in the Zif268 zinc finger-DNA complex

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

A direct comparison of the properties of natural and designed zinc-finger proteins

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https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Human zinc fingers as building blocks in the construction of artificial transcription factors.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Positive and negative regulation of endogenous genes by designed transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Mammalian gene targeting with designed zinc finger nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

DNA recognition by Cys2His2 zinc finger proteins

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Custom zinc-finger nucleases for use in human cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Validated zinc finger protein designs for all 16 GNN DNA triplet targets

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Engineering polydactyl zinc-finger transcription factors

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https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

FokI dimerization is required for DNA cleavage

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Efficient gene targeting in Drosophila with zinc-finger nucleases

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

High-throughput beta-galactosidase assay for bacterial cell-based reporter systems

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.20

7 January 2021

Identifiers

DOI

10.1038/MT.2008.20

1 reference

16 September 2017

1 reference