(Q28265983)

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

21 April 2017

1 reference

Genetic manipulation of genomes with rare-cutting endonucleases

21 April 2017

1 reference

Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates

21 April 2017

1 reference

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

21 April 2017

1 reference

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 April 2017

1 reference

Design and selection of novel Cys2His2 zinc finger proteins

21 April 2017

1 reference

Engineering polydactyl zinc-finger transcription factors

21 April 2017

1 reference

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 April 2017

1 reference

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 April 2017

1 reference

FokI dimerization is required for DNA cleavage

21 April 2017

1 reference

Chromosomal stability and the DNA double-stranded break connection

21 April 2017

1 reference

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

21 April 2017

1 reference

Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

21 April 2017

1 reference

Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

21 April 2017

1 reference

Homing endonucleases: keeping the house in order

21 April 2017

1 reference

Design, activity, and structure of a highly specific artificial endonuclease

21 April 2017

1 reference

Isolation and characterization of new homing endonuclease specificities at individual target site positions

21 April 2017

1 reference

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

21 April 2017

1 reference

Chimeric nucleases stimulate gene targeting in human cells

21 April 2017

1 reference

DNA recognition by Cys2His2 zinc finger proteins

21 April 2017

1 reference

21 April 2017

Transformation of yeast

1 reference

[12] One-step gene disruption in yeast

21 January 2018

1 reference

Yeast transformation: a model system for the study of recombination

21 January 2018

1 reference

Altering the genome by homologous recombination

21 January 2018

1 reference

Positive genetic selection for gene disruption in mammalian cells by homologous recombination

21 January 2018

1 reference

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

21 January 2018

1 reference

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

21 January 2018

1 reference

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

21 January 2018

1 reference

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

21 January 2018

1 reference

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

21 January 2018

1 reference

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

21 January 2018

1 reference

Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells

21 January 2018

1 reference

I-SceI-induced gene replacement at a natural locus in embryonic stem cells

21 January 2018

1 reference

Recognition of chromosomal DNA by PNAs

21 January 2018

1 reference

Chimeric restriction enzymes: what is next?

21 January 2018

1 reference

Chimeric restriction endonuclease

21 January 2018

1 reference

Chimeric restriction enzyme: Gal4 fusion to FokI cleavage domain

21 January 2018

1 reference

A detailed study of the substrate specificity of a chimeric restriction enzyme.

21 January 2018

1 reference

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

21 January 2018

1 reference

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

21 January 2018

1 reference

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

21 January 2018

1 reference

Pointing fingers at the limiting step in gene targeting

21 January 2018

1 reference

Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model

21 January 2018

1 reference

Drug discovery with engineered zinc-finger proteins

21 January 2018

1 reference

Frequent chromosomal translocations induced by DNA double-strand breaks

21 January 2018

1 reference

Double-strand breaks and translocations in cancer

21 January 2018

1 reference

Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

21 January 2018

1 reference

The design of functional DNA-binding proteins based on zinc finger domains.

21 January 2018

1 reference

Chromosome breaks and genomic instability

21 January 2018

1 reference

Double-strand break repair in human cells.

21 January 2018

1 reference

Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion

21 January 2018

1 reference

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

21 January 2018

1 reference

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins

21 January 2018

1 reference

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

21 January 2018

1 reference

Validated zinc finger protein designs for all 16 GNN DNA triplet targets

21 January 2018

1 reference

Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table.

21 January 2018

1 reference

Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants.

21 January 2018

1 reference

Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units

21 January 2018

1 reference

Invasion of a multitude of genetic niches by mobile endonuclease genes

21 January 2018

1 reference

A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells

21 January 2018

1 reference

Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system

21 January 2018

1 reference

EXAFS study of the zinc-binding sites in the protein transcription factor IIIA

21 January 2018

1 reference