(Q31121743)

English

Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 June 2017

Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

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inferred from title

monoclonal antibody

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based on heuristic

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5

object named as

Carlos F Barbas

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Europe PubMed Central

PubMed publication ID

29 June 2017

Christoph Rader

6

object named as

Christoph Rader

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Europe PubMed Central

PubMed publication ID

29 June 2017

author name string

Mikhail Popkov

1

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Europe PubMed Central

PubMed publication ID

29 June 2017

Rose G Mage

2

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Europe PubMed Central

PubMed publication ID

29 June 2017

Cornelius B Alexander

3

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Europe PubMed Central

PubMed publication ID

29 June 2017

Sujatha Thundivalappil

4

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Europe PubMed Central

PubMed publication ID

29 June 2017

language of work or name

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publication date

1 January 2003

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29 June 2017

number of pages

11

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Journal of Molecular Biology

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29 June 2017

325

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29 June 2017

2

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29 June 2017

325-335

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Europe PubMed Central

PubMed publication ID

29 June 2017

Biopharmaceutical benchmarks

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Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

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Making antibody fragments using phage display libraries

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Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

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In vitro display technologies: novel developments and applications

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Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

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Phage display of combinatorial antibody libraries.

1 reference

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Synthetic human antibodies

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Natural and designer binding sites made by phage display technology

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Signaling antibodies in cancer therapy

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The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies.

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Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization.

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Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

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Generation of the primary antibody repertoire in rabbits: expression of a diverse set of Igk-V genes may compensate for limited combinatorial diversity at the heavy chain locus

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Generation of heterogeneous rabbit anti-DNP antibodies by gene conversion and hypermutation of rearranged VL and VH genes during clonal expansion of B cells in splenic germinal centers

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Complex allotypes of the rabbit immnunoglobulin kappa light chains are encoded by structural alleies

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A second rabbit kappa isotype

1 reference

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Sequence of a cDNA encoding Basilea kappa light chains (K2 isotype) suggests a possible relationship of protein structure to limited expression

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7 January 2021

Lack of K1b9 light chains in Basilea rabbits is probably due to a mutation in an acceptor site for mRNA splicing

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Kappa-chain allotypes and isotypes in the rabbit: cDNA sequences of clones encoding b9 suggest an evolutionary pathway and possible role of the interdomain disulfide bond in quantitative allotype expression

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Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

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Mechanisms of angiogenesis

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CDR3 length in antigen-specific immune receptors

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Length distribution of CDRH3 in antibodies

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Fluorescence polarization and intensity kinetic studies of antifluorescein antibody obtained at different stages of the immune response

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Mapping of the duplicated rabbit immunoglobulin kappa light chain locus

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The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites

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7 January 2021

Identifiers

10.1016/S0022-2836(02)01232-9

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

ResearchGate publication ID

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